Obesity
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Obesity is associated with declines in the CETN1 and CSPP1 abundance and compromise of both sperm morphology in mice and relevant clinical samples.
|
31651332 |
2019 |
Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Calcium-binding protein S100B has been implicated in the pathology of bipolar affective disorder (BPAD) and schizophrenia (SZ).
|
21714070 |
2011 |
Malignant neoplasm of breast
|
0.060 |
Biomarker
|
disease |
BEFREE |
EF Hand Protein IBA2 Promotes Cell Proliferation in Breast Cancers via Transcriptional Control of Cyclin D1.
|
27262171 |
2016 |
Idiopathic Pulmonary Fibrosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.
|
28530639 |
2017 |
Myositis
|
0.010 |
Biomarker
|
disease |
BEFREE |
A 63 kDa skeletal muscle protein associated with eye muscle inflammation in Graves' disease is identified as the calcium binding protein calsequestrin.
|
10052680 |
1999 |
Graves Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
A 63 kDa skeletal muscle protein associated with eye muscle inflammation in Graves' disease is identified as the calcium binding protein calsequestrin.
|
10052680 |
1999 |
Tauopathies
|
0.010 |
Biomarker
|
group |
BEFREE |
A novel calcium-binding protein is associated with tau proteins in tauopathy.
|
18346207 |
2008 |
Classical galactosemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A number of genes significantly altered were further investigated in the GAL cohort including SPARC (osteonectin) and S100A8 (S100 calcium-binding protein).
|
19952866 |
2010 |
Cholangiocarcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A recent report has suggested upregulation of the calcium-binding protein S100P in cholangiocarcinoma.
|
21029254 |
2011 |
Adenocarcinoma of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
An alternatively spliced mRNA for the calcium-binding protein calretinin (CR) is present in the colon adenocarcinoma cell line WiDr.
|
8864572 |
1996 |
Malignant neoplasm of prostate
|
0.020 |
Biomarker
|
disease |
BEFREE |
Annexin II mRNA coding for a calcium binding protein was found to be absent in prostate cancer by subtractive hybridization and Northern analysis.
|
11522620 |
2001 |
Prostate carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Annexin II mRNA coding for a calcium binding protein was found to be absent in prostate cancer by subtractive hybridization and Northern analysis.
|
11522620 |
2001 |
Alzheimer Disease, Late Onset
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Calmodulin is a calcium binding protein codified by three genes, one of them (CALM3) maps to chromosome 19, nearby a gene, apoE, associated with late onset AD.
|
9237482 |
1997 |
Amyloidosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Calnuc is a Golgi resident, calcium-binding protein, identified as chaperone protein and is reported to protect the cells against the cytotoxicity caused by amyloidosis and ER stress.
|
30710272 |
2019 |
Tumor necrosis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Changes in brain gene expression levels of induced nitric oxide synthase (iNOS), astroglia marker, glial fibrillary acidic protein (GFAP), ionized calcium-binding protein (Iba1) a microglia activation marker, a pro-inflammatory mediator and tumor necrosis alpha (TNF-α) were measured after withdrawal by real-time polymerase chain reaction (RT-PCR).
|
28654797 |
2017 |
Non-Small Cell Lung Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Clinical significance of calcium-binding protein S100A8 and S100A9 expression in non-small cell lung cancer.
|
29733516 |
2018 |
Acute Cerebrovascular Accidents
|
0.010 |
Biomarker
|
disease |
BEFREE |
Clinical, imagiology, laboratory (biomarkers: C-reactive protein, D-dimer, and fibrinogen, and S100 calcium binding protein β [S100β]), and functionality assessments were conducted four different times: within 24 hours, and at 48 hours, 3 weeks, and 12 weeks after acute stroke.
|
30213243 |
2018 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Consideration of clinical studies in conjunction with evidence from experimental animal models reveals that the tyrosine kinase receptor erbB1/EGFR, the calcium binding protein S100A4 and the the cell cycle arrest/apoptosis-inducing p53 protein are amongst the most promising targets for therapy against metastatic disease in patients with bladder cancer.
|
12792907 |
2003 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.
|
30822709 |
2019 |
Malignant neoplasm of prostate
|
0.020 |
Biomarker
|
disease |
BEFREE |
DNA methylation and immunohistochemical analysis of the S100A4 calcium binding protein in human prostate cancer.
|
17219414 |
2007 |
Prostate carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
DNA methylation and immunohistochemical analysis of the S100A4 calcium binding protein in human prostate cancer.
|
17219414 |
2007 |
Malignant neoplasm of stomach
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.
|
25266115 |
2015 |
Stomach Carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.
|
25266115 |
2015 |
Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Dysregulation of pyramidal cell network function by the soma- and axon-targeting inhibitory neurons that contain the calcium-binding protein parvalbumin (PV) represents a core pathophysiological feature of schizophrenia.
|
24628518 |
2015 |
Malignant Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Elevated levels of the calcium-binding protein S100A4 promote metastasis and in carcinoma cells are associated with reduced survival of cancer patients.
|
19917604 |
2010 |