|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Duality of statin action on lipoprotein subpopulations in the mixed dyslipidemia of metabolic syndrome: Quantity vs quality over time and implication of CETP.
|
29574070 |
2019 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Significant changes in hepatic transcriptome and circulating miRNAs are associated with diet-induced metabolic syndrome in apoE3L.CETP mice.
|
31016757 |
2019 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Here we use an existing computational modelling framework describing the long-term development of Metabolic Syndrome (MetS) in APOE3L.CETP mice fed a high-fat diet containing cholesterol with a human-like metabolic system.
|
30808366 |
2019 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Given that ApoE3L.CETP mice were extensively studied to describe the MetS, and given that RYGB improved ceramide after surgery, our data confirmed the usefulness of ApoE3L.CETP mice after RYGB in deciphering the metabolic improvements to treat the MetS.
|
31270430 |
2019 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to examine the effect of CETP polymorphisms (rs5882 and rs3764261) and macronutrient intakes interaction in relation to metabolic syndrome (MetS) or its components.
|
29942448 |
2018 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Our data support the notion that the consumption of a Mediterranean diet may play a contributing role in triggering lipid metabolism by interacting with the rs3764261 SNP at CETP gene locus in MetS patients.
|
28057378 |
2018 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Mechanisms of metabolic syndrome (MetS) causation are complex, genetic and environmental factors are important factors for the pathogenesis of MetS In this study, we aimed to evaluate familial and genetic influences on metabolic syndrome risk factor and also assess association between FTO (rs1558902 and rs7202116) and CETP(rs1864163) genes' single nucleotide polymorphisms (SNP) with low HDL_C in the Tehran Lipid and Glucose Study (TLGS).
|
29548861 |
2018 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
The ApoE*3Leiden.CETP mouse model overcomes part of this limitation, since they have a humanised lipoprotein metabolism and a heterogeneous response to MetS, similar to humans.
|
29975550 |
2018 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Association between Six CETP Polymorphisms and Metabolic Syndrome in Uyghur Adults from Xinjiang, China.
|
28629169 |
2017 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
To determine the relationship between polymorphism and lipid profile, we measured lipids and CETP concentration in metabolic syndrome and control subjects.
|
27496123 |
2016 |
|
Metabolic Syndrome X
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Both PCSK9 levels and CETP activity were higher in patients with an increasing number of MetS components.
|
27488210 |
2016 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Our study indicates that the APOA5, BUD13, CETP, and LIPA genes may contribute to the risk of MetS independently as well as through gene-gene and gene-environment interactions.
|
27827461 |
2016 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Finally, we replicated the LPL and CETP loci previously found to be associated with MetS in Europeans.
|
26507551 |
2015 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
This suggests that CETP TaqIB and ApoE polymorphisms may not be considered as genetic risk factors for MetS in a Southern Thai population.
|
26014924 |
2015 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
In conclusion, our results show the involvement of the variants of ESR1, LPL and CETP genes in metabolic events related to MetS or some of its features.
|
26370976 |
2015 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome.
|
24373179 |
2014 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To determine the relationship between -629C/A polymorphism and lipid levels, lipids and CETP concentration were measured in metabolic syndrome and normal subjects.
|
22729881 |
2012 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
|
21386085 |
2011 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
GWASCAT |
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
|
21386085 |
2011 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
We assessed lipid levels and the frequencies of the cholesteryl ester transfer protein (CETP) Taq-1 B, lipoprotein lipase (LPL)S447X, -93 T/G, apolipoprotein B (APO B) 96bp ins/del, lipoprotein(a) (LP[a]) pentanucleotide repeat, and apolipoprotein E (APO) E epsilon 2/3/4 polymorphisms in relation to the metabolic syndrome using both National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and International Diabetes Federation (IDF) definitions.
|
19642912 |
2009 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The Taq1B-variant in the cholesteryl ester-transfer protein gene and the risk of metabolic syndrome.
|
18239576 |
2008 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
BEFREE |
Genetics linked to a defined pathology and its corresponding drug therapies is exemplified by ADRB1, ACE, CETP and APOE and drug response in metabolic syndrome.
|
15469403 |
2004 |
|
Metabolic Syndrome X
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
We investigated the association of the TaqIB CETP polymorphism and various parameters of the insulin resistance syndrome in a cross sectional population based study.
|
15589073 |
2004 |