Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE IQGAP2 was recently reported as a tumor suppressor of prostate cancer (PC). 30428404 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE IQGAP1 has been suggested to be an oncogene, while IQGAP2 is considered a tumor-suppressor gene. 27488117 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE Thus, these data identified IQGAP2 as a novel tumor suppressor for ovarian cancer to inhibit cell invasion through regulating Wnt/β-catenin signaling, and provided a new biomarker and potential therapeutic strategy for this disease. 26549344 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 AlteredExpression group BEFREE Negative IQGAP2 expression was significantly associated with larger tumor size (p=0.009), multicentric tumor occurrence (p=0.01), advanced TNM stage (0.009) and tumor differentiation (III and IV, p=0.020). 24998570 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE We also demonstrated that Iqgap2(-/-) hepatic tumors shared genetic signatures with HCC tumors from patients with advanced disease as evidenced by a 78% mouse-to-human microarray data set concordance rate with 117 out of 151 identified ortholog genes having similar expression profiles across the two species. 23951254 2013
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE We report here that IQGAP2 is a candidate tumour suppressor of prostate cancer (PC). 22406297 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.070 Biomarker group BEFREE The cumulative evidence suggests IQGAP1 is an oncogene while IQGAP2 may be a tumor suppressor. 19433088 2009