CFTR, CF transmembrane conductance regulator, 1080

N. diseases: 476; N. variants: 673
Disease: Duodenal Ulcer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013295
Disease: Duodenal Ulcer
Duodenal Ulcer 		0.210 AlteredExpression disease BEFREE H. pylori infection downregulates duodenal epithelial cellular CFTR and SLC26A6 expressions through TGFβ-mediated P38 MAPK signaling pathway, which contributes to further elucidating the pathogenesis of H. pylori-associated duodenal ulcer. 30119655 2018
CUI: C0013295
Disease: Duodenal Ulcer
Duodenal Ulcer 		0.210 Biomarker disease RGD A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats. 15905414 2005