CFTR, CF transmembrane conductance regulator, 1080

N. diseases: 476; N. variants: 673
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE This review summarizes our present knowledge of how influenza virus infections alter airway and alveolar epithelial cell CFTR and ENaC function in vivo and in vitro and the role of these changes in influenza pathogenesis. 28775098 2017
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection. 25795456 2015
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE Viral infection caused the nanoscale microdomains to fuse into large platforms and reduced CFTR mobility. 26153705 2015
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 GeneticVariation group BEFREE Thus, we surmised that factors enlisted to process misfolded proteins such as ΔF508-CFTR in the secretory pathway also act to restrict viral infection. 21625534 2011