DisGeNET - a database of gene-disease associations

SDCCAG8, serologically defined colon cancer antigen 8, 10806

N. diseases: 90; N. variants: 44

Disease: Chronic kidney disease stage 5 ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C2316810
Disease:	Chronic kidney disease stage 5

Chronic kidney disease stage 5

0.120

GeneticVariation

disease

BEFREE

We conclude that NGS is extremely useful in the identification of SDCCAG8-related NPHP as a cause of sudden-onset ESKD during infancy.

31534065

2019

CUI:	C2316810
Disease:	Chronic kidney disease stage 5

Chronic kidney disease stage 5

0.120

GeneticVariation

disease

BEFREE

Variants in NPHS2, SDCCAG8 and near BMP4 appear to interact with APOL1 to modulate the risk for non-diabetic ESKD in AAs.

24157943

2014

CUI:	C2316810
Disease:	Chronic kidney disease stage 5

Chronic kidney disease stage 5

0.120

Biomarker

disease

HPO