DHRS4, dehydrogenase/reductase 4, 10901

N. diseases: 5; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 AlteredExpression phenotype BEFREE In addition, we found that low <i>DHRS4-AS1</i> expression was significantly associated with a high tumor node metastasis stage, lymph node metastasis, advanced pathological grade and poor prognosis. 30254456 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE Taken together, our findings identify the role of <i>DHRS4-AS1</i> as a tumor inhibitor in ccRCC for the first time, demonstrating that <i>DHRS4-AS1</i> is a potential prognostic biomarker that could potentially be applied in ccRCC therapy. 30254456 2018
Conventional (Clear Cell) Renal Cell Carcinoma
0.010 Biomarker disease BEFREE Taken together, our findings identify the role of <i>DHRS4-AS1</i> as a tumor inhibitor in ccRCC for the first time, demonstrating that <i>DHRS4-AS1</i> is a potential prognostic biomarker that could potentially be applied in ccRCC therapy. 30254456 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.010 Biomarker phenotype BEFREE These data indicate that <i>DHRS4-AS1</i> functions by preventing the proliferation and invasion, inhibiting the cell cycle progression and promoting the apoptosis of ccRCC cells. 30254456 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 GeneticVariation disease LHGDN Expression of a novel alternatively spliced variant of NADP(H)-dependent retinol dehydrogenase/reductase with deletion of exon 3 in cervical squamous carcinoma. 17230527 2007