UTS2, urotensin 2, 10911

N. diseases: 115; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.030 Biomarker disease BEFREE Urotensin II is a putative mediator of the effects of the adrenal medulla and pheochromocytoma on the adrenocortical zona glomerulosa. 19001524 2009
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.030 Biomarker disease BEFREE Thus, UII and its receptor GPR14 exert a possible effect in the pathogenesis of pheochromocytoma. 17102097 2006
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.030 AlteredExpression disease BEFREE The reverse transcriptase polymerase chain reaction (RT-PCR) showed expression of urotensin II and its receptor mRNAs in all the samples examined; seven pheochromocytomas, nine adrenocortical adenomas (four with primary aldosteronism, four with Cushing syndrome and one with non-functioning adenoma), four adrenocortical carcinomas, one ganglioneuroblastoma and five neuroblastomas, as well as four normal portions of adrenal glands (cortex and medulla). 12668216 2003