Systemic candidiasis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
According to data from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) 2010, Candida tropicalis (C. tropicalis) is the third most common pathogen causing invasive candidiasis.
|
25533826 |
2014 |
Invasive Candidiasis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
According to data from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) 2010, Candida tropicalis (C. tropicalis) is the third most common pathogen causing invasive candidiasis.
|
25533826 |
2014 |
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Overexpression of CDC7 and its protein regulator DBF4 is highly neurotoxic and promotes cancer and neurodegeneration.
|
29984527 |
2018 |
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
However, the downstream targets of Cdc7-Dbf4 contributed to checkpoint regulation and replication stress-support function in cancer are not fully identified.
|
29209046 |
2017 |
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach.
|
30293817 |
2018 |
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach.
|
30293817 |
2018 |
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
However, the downstream targets of Cdc7-Dbf4 contributed to checkpoint regulation and replication stress-support function in cancer are not fully identified.
|
29209046 |
2017 |
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
Overexpression of CDC7 and its protein regulator DBF4 is highly neurotoxic and promotes cancer and neurodegeneration.
|
29984527 |
2018 |
melanoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
In summary, our study not only elucidated that ASK/Dbf4, a novel cell survival gene in melanoma was transcriptionally regulated by E2F1, but also that the induction of ASK/Dbf4 was refractory to UVB exposure suggesting that its upregulation was not an early event in melanomagenesis.
|
18503552 |
2008 |
melanoma
|
0.020 |
Biomarker
|
disease |
LHGDN |
In summary, our study not only elucidated that ASK/Dbf4, a novel cell survival gene in melanoma was transcriptionally regulated by E2F1, but also that the induction of ASK/Dbf4 was refractory to UVB exposure suggesting that its upregulation was not an early event in melanomagenesis.
|
18503552 |
2008 |
Systemic candidiasis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Here we report on surveillance for IC from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study.
|
29743305 |
2018 |
Invasive Candidiasis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Here we report on surveillance for IC from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study.
|
29743305 |
2018 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Functional interaction between tumor suppressor menin and activator of S-phase kinase.
|
15374998 |
2004 |
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Cdc7-Dbf4 kinase (Dbf4-dependent kinase, DDK) is an essential factor of DNA replication and DNA damage response (DDR), which is associated with tumorigenesis.
|
23684929 |
2013 |
Candidemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Candida parapsilosis was the most common species causing candidemia in the 2010 China Hospital Invasive Fungal Surveillance Net (CHIF-NET) database.
|
26282840 |
2015 |
Invasive Fungal Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
Five-year China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study of invasive fungal infections caused by noncandidal yeasts: species distribution and azole susceptibility.
|
30349323 |
2018 |
Malignant Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Both CDC7 and DBF4 promoters bind E2F, suggesting that increased E2F activity in RB1 mutant cancers promotes increased DDK expression.
|
28448802 |
2017 |
melanoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In summary, we report the differential regulation of a novel gene, namely ASK/Dbf4, in melanoma and suggest that up-regulation of ASK/Dbf4 is a novel molecular determinant with prognostic relevance that confers a proliferative advantage in cutaneous melanoma.
|
17768177 |
2007 |
melanoma
|
0.020 |
AlteredExpression
|
disease |
LHGDN |
In summary, we report the differential regulation of a novel gene, namely ASK/Dbf4, in melanoma and suggest that up-regulation of ASK/Dbf4 is a novel molecular determinant with prognostic relevance that confers a proliferative advantage in cutaneous melanoma.
|
17768177 |
2007 |
Cutaneous Melanoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In summary, we report the differential regulation of a novel gene, namely ASK/Dbf4, in melanoma and suggest that up-regulation of ASK/Dbf4 is a novel molecular determinant with prognostic relevance that confers a proliferative advantage in cutaneous melanoma.
|
17768177 |
2007 |
Cutaneous Melanoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Recently, we have reported the differential regulation of a novel gene, namely ASK/Dbf4, in melanoma and suggested upregulation of ASK/Dbf4 as a novel molecular determinant with prognostic relevance that confers a proliferative advantage in cutaneous melanoma.
|
18503552 |
2008 |