Primary Sjögren's syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
CEP-1 is a major antigenic target of ACPA in patients with pSS characterizing a subgroup with distinct laboratory features.
|
28919520 |
2017 |
Leukemogenesis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Molecular genetic analyses of these model mice, as well as primary human disease, demonstrated that CNTRL-FGFR1, through abnormal activation of several signaling pathways related to development and differentiation of both myeloid and T-lymphoid cells, contribute to overt leukemogenesis.
|
23777766 |
2013 |
Primary Effusion Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
An methylthiotetrazole assay revealed that the cell proliferation of PEL cell lines was significantly suppressed by the addition of CEP (1-10 microg/ml).
|
19521981 |
2009 |
Milroy Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
To explore the molecular cytogenetic abnormalities in Chinese patients with PCL, interphase FISH studies with three probes for the regions containing 13q14.3 (D13S319), 14q32 (IGHC/IGHV) and 1q12(CEP1) were retrospectively performed in 21 PCL patients.
|
18284415 |
2009 |
Chromosome 11p11.2 Deletion Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our aim is to determine the prevalence of anti-CEP-1 in a cohort of ACPA positive (ACPA+) primary Sjogren's syndrome (pSS) patients.
|
28919520 |
2017 |
PEELING SKIN SYNDROME
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our aim is to determine the prevalence of anti-CEP-1 in a cohort of ACPA positive (ACPA+) primary Sjogren's syndrome (pSS) patients.
|
28919520 |
2017 |
Early Inflammatory Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results suggest that a-CEP-1 may help in differentiation between RF(-) RA and UA. a-CEP-1 and a-Sa may be useful while diagnosing EIA. a-CarP may be used in differentiation of RA RF(-) and UA.
|
30406565 |
2019 |
Cytokine Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
|
22610502 |
2012 |
Cytokine Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
|
22610502 |
2012 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In B16 mouse melanoma cells, FAN was downregulated and the impact on FAN on cell motility and invasion was determined using in vitro assays and in vivo animal models.
|
23674089 |
2013 |
Myeloproliferative disease
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Common features of myeloproliferative disorders with t(8;9)(p12;q33) and CEP110-FGFR1 fusion: report of a new case and review of the literature.
|
18096225 |
2008 |
Myeloproliferative disease
|
0.030 |
GeneticVariation
|
group |
BEFREE |
FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33).
|
10688839 |
2000 |
Myeloproliferative disease
|
0.030 |
GeneticVariation
|
group |
BEFREE |
NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder.
|
15087377 |
2004 |
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.
|
23777766 |
2013 |
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Based on our recent findings that the TNF receptor adaptor protein FAN mediates TNF-induced actin reorganisation and regulates the directed migration of immune cells responding to chemotactic cues, we addressed the role of FAN in cancer cell motility and the formation of invadopodia, a crucial feature in tumour invasion.
|
23674089 |
2013 |
Lung Diseases, Interstitial
|
0.020 |
Biomarker
|
group |
BEFREE |
Anti-CEP-1 antibodies may represent a useful biomarker for RA-associated ILD and erosive disease to be employed in clinical practice.
|
29452423 |
2018 |
Lung Diseases, Interstitial
|
0.020 |
Biomarker
|
group |
BEFREE |
Significant associations were identified between anti-CEP-1 and joint erosions at anti-CEP-1 value of >124.78 U/ml (p = .0026) and between anti-CEP-1 and ILD at anti-CEP-1 value of >185.91 U/ml (p = .0222).
|
30611755 |
2019 |
Autoimmune Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Antibodies to citrullinated proteins are associated with HLA 'shared epitope' alleles, and autoimmunity to at least one antigenic sequence, the CEP-1 peptide from citrullinated alpha-enolase (KIHAcitEIFDScitGNPTVE), shows a specific association with HLA-DRB1*0401, *0404, 620W PTPN22, and smoking.
|
20192991 |
2010 |
Congenital chromosomal disease
|
0.010 |
GeneticVariation
|
group |
BEFREE |
To explore the molecular cytogenetic abnormalities in Chinese patients with PCL, interphase FISH studies with three probes for the regions containing 13q14.3 (D13S319), 14q32 (IGHC/IGHV) and 1q12(CEP1) were retrospectively performed in 21 PCL patients.
|
18284415 |
2009 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The results of our study suggest that FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of TNF.
|
23674089 |
2013 |
Lower respiratory tract infection
|
0.010 |
Biomarker
|
group |
BEFREE |
NGAL, rather than CEP-1, may be appealing adjuncts for diagnosis of LRTIs.
|
31672649 |
2020 |
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Based on our recent findings that the TNF receptor adaptor protein FAN mediates TNF-induced actin reorganisation and regulates the directed migration of immune cells responding to chemotactic cues, we addressed the role of FAN in cancer cell motility and the formation of invadopodia, a crucial feature in tumour invasion.
|
23674089 |
2013 |
Eosinophilic disorder
|
0.010 |
GeneticVariation
|
group |
BEFREE |
8p11 myeloproliferative syndrome preceded by t(8;9)(p11;q33), CEP110/FGFR1 fusion transcript: morphologic, molecular, and cytogenetic characterization of myeloid neoplasms associated with eosinophilia and FGFR1 abnormality.
|
18295660 |
2008 |