Disease: Endometrial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.330 GeneticVariation disease BEFREE Here, we characterise the effects of CHD4 mutations identified in endometrial carcinoma on the remodelling properties of dMi-2, the highly conserved Drosophila homologue of CHD4. 29844320 2018
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.330 GeneticVariation disease BEFREE CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling. 29888111 2018
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.330 GeneticVariation disease BEFREE For the first time, we show that mutations in chromatin remodelling-related genes (KMT2D, KMT2C, SETD1B and BCOR) and in DNA-repair-related genes (BRCA1, BRCA2, RAD50 and CHD4) are frequent in this subtype of endometrial cancer. 27997699 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.330 Biomarker disease CTD_human Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes. 23104009 2012