Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280781
Disease: Adult Pilocytic Astrocytoma
Adult Pilocytic Astrocytoma
0.010 Biomarker disease BEFREE Brain 123I-FP-CIT SPECT of a Holmes Tremor Due to Midbrain Pilocytic Astrocytoma. 31306206 2020
CUI: C0334583
Disease: Pilocytic Astrocytoma
Pilocytic Astrocytoma
0.010 Biomarker disease BEFREE Brain 123I-FP-CIT SPECT of a Holmes Tremor Due to Midbrain Pilocytic Astrocytoma. 31306206 2020
CUI: C0750940
Disease: Tremor, Rubral
Tremor, Rubral
0.010 Biomarker disease BEFREE Brain 123I-FP-CIT SPECT of a Holmes Tremor Due to Midbrain Pilocytic Astrocytoma. 31306206 2020
CUI: C1332995
Disease: Childhood Pilocytic Astrocytoma
Childhood Pilocytic Astrocytoma
0.010 Biomarker disease BEFREE Brain 123I-FP-CIT SPECT of a Holmes Tremor Due to Midbrain Pilocytic Astrocytoma. 31306206 2020
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 AlteredExpression disease BEFREE Knockdown of CIT-K expression also inhibited breast cancer cell migration and invasion capacity. 30565087 2019
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior
0.010 GeneticVariation phenotype BEFREE We performed <sup>123</sup> I-FP-CIT Single-photon emission computed tomography (SPECT) and correlated DAT binding ratios in the bilateral caudate and putamen with gambling symptoms (G-SAS, PG-YBOCS) and behaviors, as well as other psychometric variables (anhedonia and impulsivity). 30226290 2019
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.010 Biomarker disease BEFREE This study provides the rationale for CIT being a potential therapeutic target in MM in future trials. 30940634 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 Biomarker phenotype BEFREE The expression of a two-gene set, CIT and HSPB8 with an overall balanced accuracy of 98.8% and a threshold value of 0.2347, was sufficient to classify metastasis. 31273254 2019
CUI: C0030662
Disease: Gambling, Pathological
Gambling, Pathological
0.010 GeneticVariation disease BEFREE Striatal presynaptic dopaminergic dysfunction in gambling disorder: A <sup>123</sup> I-FP-CIT SPECT study. 30226290 2019
CUI: C0178417
Disease: Anhedonia
Anhedonia
0.010 GeneticVariation disease BEFREE We performed <sup>123</sup> I-FP-CIT Single-photon emission computed tomography (SPECT) and correlated DAT binding ratios in the bilateral caudate and putamen with gambling symptoms (G-SAS, PG-YBOCS) and behaviors, as well as other psychometric variables (anhedonia and impulsivity). 30226290 2019
CUI: C0268070
Disease: Hypocupremia
Hypocupremia
0.010 Biomarker disease BEFREE Green synthesis of 1,4-disubstituted-1,2,3-triazoles via click reaction using nano magnetic Fe<sub>3</sub>O<sub>4</sub> core decorated with cyclodextrin-citric acid (Fe<sub>3</sub>O<sub>4</sub>@CD-CIT) acting as a phase transfer nanoreactor with low copper loading under ultrasonication at 40 °C, in aqueous media is described. 31299591 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.010 GeneticVariation disease BEFREE Cognition was measured using the Six-Item Cognitive Impairment Test (6-CIT). 31220173 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.010 Biomarker phenotype BEFREE Citron kinase (CIT-K) promotes aggressiveness and tumorigenesis of breast cancer cells in vitro and in vivo: preliminary study of the underlying mechanism. 30565087 2019
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer
0.010 Biomarker disease BEFREE Univariate and multivariate analyses indicated that adjuvant CIT was an independent prognostic factor for the OS of patients with EOC. 30713783 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 AlteredExpression disease BEFREE Knockdown of CIT-K expression also inhibited breast cancer cell migration and invasion capacity. 30565087 2019
CUI: C0854776
Disease: Pancreatic carcinoma non-resectable
Pancreatic carcinoma non-resectable
0.010 Biomarker disease BEFREE Furthermore, the CIT group exhibited a significantly higher overall survival rate for patients with unresectable metastatic pancreatic cancer compared with the TACE and control groups (P=0.0088 and P<0.0001, respectively), which suggests that a combination of different interventional techniques increases the survival of patients with unresectable pancreatic cancer. 31289509 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.010 AlteredExpression phenotype BEFREE Knockdown of CIT-K expression also inhibited breast cancer cell migration and invasion capacity. 30565087 2019
CUI: C3887938
Disease: Deuteranomaly
Deuteranomaly
0.010 Biomarker disease BEFREE This image highlights that the early phases of F-FP-CIT PET may reflect regional cerebral perfusion with a pattern very similar to that of regional glucose metabolism in CBD. 30371594 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.010 Biomarker disease BEFREE In the subgroup of patients not on DRT (n=81), we found a significant negative association between anxiety and thalamic <sup>123</sup>I-FP-CIT binding ratios bilaterally (right: β=-0.349, p=0.001, ΔR<sup>2</sup>=0.119; left: β=-0.269, p=0.017, ΔR<sup>2</sup>=0.071) (p<sub>corr</sub> <0.020). 28899958 2018
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.010 Biomarker group BEFREE In the subgroup of patients not on DRT (n=81), we found a significant negative association between anxiety and thalamic <sup>123</sup>I-FP-CIT binding ratios bilaterally (right: β=-0.349, p=0.001, ΔR<sup>2</sup>=0.119; left: β=-0.269, p=0.017, ΔR<sup>2</sup>=0.071) (p<sub>corr</sub> <0.020). 28899958 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker disease BEFREE This retrospective study aimed to determine the clinical outcomes following particle monotherapy (ie, proton therapy [PT] or carbon ion therapy [CIT]) in patients with sinonasal squamous cell carcinoma at a single institution. 29859787 2018
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.010 Biomarker disease BEFREE The association of quantitatively analyzed <sup>123</sup>I-FP-CIT binding in striatal subregions with the development of motor fluctuations, dyskinesias, freezing of gait (FOG) and falls as well as the time to Hoehn and Yahr (H&Y) stage 3 was evaluated. 29801899 2018
CUI: C0013720
Disease: Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome
0.010 Biomarker disease BEFREE We assessed and compared semi-quantified [<sup>123</sup>I]FP-CIT SPECT, and motor and non-motor features among these two groups, alongside exploring the clinical and imaging correlates of EDS and the predictive significance of these markers in the development of EDS. 29571867 2018
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.010 Biomarker disease BEFREE Because CIT was more firmly combined with RANKL than IT, CIT had stronger anti-osteoporosis effect by inhibiting bone resorption. 30036771 2018
CUI: C0032897
Disease: Prader-Willi Syndrome
Prader-Willi Syndrome
0.010 Biomarker disease BEFREE Mean brain-stem 5-HTT availability determined by [123I]-beta-CIT single photon emission tomography was lower in eight adults with mUPD PWS compared with nine adults with del PWS (mean difference -0.93, t = -2.85, P = 0.014). 29433608 2018