FOXN3, forkhead box N3, 1112

N. diseases: 40; N. variants: 13
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 Biomarker disease BEFREE Forkhead box N3 (FOXN3) has been reported to be downregulated in numerous cancers, including laryngeal, oral squamous cell and hepatocellular carcinomas, and diffuse large B‑cell lymphoma. 30483801 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 GeneticVariation disease BEFREE FOXN3 is a tumor suppresser and alterations in FOXN3 are found in of a variety of cancers including melanoma, osteosarcoma, and hepatocellular carcinoma. 31214487 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 AlteredExpression disease BEFREE Collectively, our findings indicate that FOXN3 functions as a tumor suppressor in HCC by downregulating the expression of E2F5. 27259277 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 Biomarker disease LHGDN Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets. 17983802 2007