CAPN10, calpain 10, 11132

N. diseases: 58; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.040 Biomarker phenotype BEFREE These findings provided some evidence that CAPN10 gene may play an important role in the pathogenesis of IFG/IGT in EH patients. 20406624 2010
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.040 AlteredExpression phenotype BEFREE However, after a 24-h infusion of Intralipid, we noted a significant increase in CAPN10 mRNA in response to insulin in subjects with NGT but not in subjects with IGT. 16186407 2005
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.040 Biomarker phenotype BEFREE These results indicate the contribution of SNP-19 in CAPN10 to mild obesity and glucose intolerance in Japanese. 14500039 2003
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.040 GeneticVariation phenotype BEFREE This study supports the paradigm that specific haplotype combinations of calpain 10 variants increase risk of both IFG/IGT and type 2 diabetes. 11978665 2002