Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.070 AlteredExpression disease BEFREE The endpoint of interest was major adverse cardiac event (MACE), including all-cause death, recurrent myocardial infarction, and hospitalization for heart failure.Patients with elevated serum YKL-40 levels (≥126.8 ng/mL) were more likely to be older and smoker and to present with type 2 diabetes, advanced Killip class, multivessel disease and intra-aortic balloon pump, with increased levels of admission glucose, triglyceride, and high-sensitivity C-reactive protein and decreased level of high-density lipoprotein cholesterol. 30896649 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.070 AlteredExpression disease BEFREE Elevated YKL-40 level at baseline is associated with later development of type 2 diabetes. 30328100 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.070 AlteredExpression disease BEFREE Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine. 28841871 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.070 Biomarker disease BEFREE Circulating miRNA-24 and its target YKL-40 as potential biomarkers in patients with coronary heart disease and type 2 diabetes mellitus. 28968969 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.070 Biomarker disease BEFREE The inflammatory biomarker YKL-40 seems to play a role in atherosclerosis and is elevated in patients with obesity, cardiovascular disease and type 2 diabetes. 23071724 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.070 Biomarker disease BEFREE YKL-40 is involved in inflammatory processes and patients with Type 2 Diabetes (T2D) have elevated circulating YKL-40 levels which correlate with their level of insulin resistance. 19421404 2009
Diabetes Mellitus, Non-Insulin-Dependent
0.070 AlteredExpression disease BEFREE Within the groups with normal glucose tolerance and type 2 diabetes, obesity subgroups showed no difference with respect to either plasma YKL-40 or adipose tissue YKL-40 mRNA levels. 18650368 2008