FSTL1, follistatin like 1, 11167

N. diseases: 128; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 Biomarker disease BEFREE In this study, we elucidated the potential mechanisms by which FSTL1 contributes to the pathogenesis of RA. 29932210 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 Biomarker disease BEFREE During cancer progression and rheumatoid arthritis, controversial data have been reported with respect to the proliferative, apoptotic, migratory, and inflammatory effects of FSTL1. 29594389 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 Biomarker disease BEFREE Meanwhile, the expression of follistatin-like protein 1 (FSTL1) was upregulated, which suggests that FSTL1 plays a key role in RA development. 27498552 2016
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 AlteredExpression disease BEFREE Follistatin-like 1 (FSTL1) was identified as a novel pro-inflammatory protein showing high-level expression in rheumatoid arthritis. 26716515 2016
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 AlteredExpression disease LHGDN Follistatin-like protein 1 promotes arthritis by up-regulating IFN-gamma. 19109154 2009
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 AlteredExpression disease BEFREE Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis. 16735027 2006
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 AlteredExpression disease LHGDN Follistatin-related protein gene (FRP) is expressed in the synovial tissues of rheumatoid arthritis, but its polymorphisms are not associated with genetic susceptibility. 15638044 2005
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 Biomarker disease BEFREE To examine the expression level and function of follistatin-related protein gene (FRP, also referred to as FSTL1) in rheumatoid arthritis (RA), and possible association of its polymorphisms with genetic susceptibility to RA. 15638044 2005
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.080 AlteredExpression disease BEFREE However, there was no difference between these groups in the amount of synovial FRP, suggesting its elevated turnover in RA. 9786430 1998