|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Here we aim to investigate the role of miR-198, a broad-spectrum tumor suppressor, in gastric cancer (GC).
|
31138759 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Results showed that miR-198-5p was under-expressed in NSCLC tissues and was negatively correlated with tumour size, lymph node metastasis and tumour-node-metastasis stage, while FUT8 expression was highly upregulated.
|
31381176 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In vivo tumor formation in athymic nude mice was examined using LNCaP xenografts with stable overexpression conferred using lentiviral miR‑198 transduction.
|
31322262 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
For this purpose, a tumor suppressor miRNA (miR-198), deregulated in several human cancer types, was chosen as the model oligonucleotide.
|
30765836 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In vivo study indicated that the silencing of hsa_circ_0025039 inhibits melanoma tumor formation and downregulates miR-198 and CDK4 expression.
|
30219673 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A significant increase of FSTL1 was seen in human CRC as compared to the surrounding non-tumor tissues and this occurred at both RNA and protein level.
|
30131854 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
FSTL1 plays a tumor suppression role possibly via repressing the NF-κB and HIF-2α signaling pathways.
|
29357946 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Altogether, our results revealed the critical tumor-suppression function of FSTL1 in NSCLC progression, suggesting that FSTL1 might be an important factor in NSCLC progression.
|
29115636 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
All together, our results suggest the absence of the miR-198 and -206 as powerful predictive biomarkers of the tumor cell dissemination and the rationale of their potential therapeutic use in the treatment of Osteosarcoma.
|
30515265 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
FSTL1 overexpression was apparently associated with larger tumor size, advanced TNM staging, portal vein invasion, intra-hepatic metastases.
|
28655132 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Combinatory target prediction identified tenascin C as a predicted target of miR-198, one of the top 10 miRNAs downregulated in tumour stroma of CRCs with synchronous liver metastasis.
|
29065427 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The protein level of FSTL1 was decreased in primary NPC tumors and was associated with downregulated interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α).
|
26918942 |
2016 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Decreased miR-198 expression was significantly associated with larger tumor size, deeper invasion depth, positive lymph node metastasis, advanced tumor-node-metastasis (TNM) stage, and shorter overall survival.
|
26852230 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In nude mice miR-198 inhibits A549 growth of tumor graft.
|
24357456 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8.
|
25174450 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Reconstitution of miR-198 in pancreatic cancer cells results in reduced tumor growth, metastasis, and increased survival through direct targeting MSLN, PBX-1, and VCP.
|
23989979 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our findings suggested that a tumor suppressor role of FSTL1 may be important in ovarian and endometrial carcinogenesis.
|
18796737 |
2009 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
OCC1-SEAP cells were injected s.c. or intraperitoneally into nude mice and tumor volume was measured as well as plasma SEAP levels as the tumors developed.
|
11862422 |
2002 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our analyses of human genome sequences syntenic to these regions suggest that CYP24, PFDN4, STMN1, CDKN1B, PPP2R3 and FSTL1 are candidate oncogenes or tumor-suppressor genes.
|
11694878 |
2001 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We found a correlation between expression of TSC-36 and cell growth: TSC-36 mRNA was not detected in cells derived from small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but was detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.
|
10814877 |
2000 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Histological evaluation of xenografts from OCC1 in the 33th passage implanted and grown in nude (athymic) mice revealed a morphology identical to that of the original tumor.
|
2354825 |
1990 |