Diabetic Retinopathy
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
This study showed that the rs1002630 of CHN2 were associated with DR risk and non-proliferative DR risk in Taiwanese individuals with type 2 diabetes.
|
24854763 |
2015 |
Diabetic Retinopathy
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
CPVL/CHN2 rs39059 was also associated with levels of diabetic retinopathy (P = 0.0007 for trend).
|
21911749 |
2011 |
Rheumatoid Arthritis
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
We found that BCH exposure reduced the phosphorylation of mTOR and its downstream target 4EBP1, radiolabeled leucine uptake, and migration of RA FLS.
|
29198077 |
2018 |
Nonproliferative diabetic retinopathy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients.
|
24854763 |
2015 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study showed that the rs1002630 of CHN2 were associated with DR risk and non-proliferative DR risk in Taiwanese individuals with type 2 diabetes.
|
24854763 |
2015 |
Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Therapy regime and risk classification were based on COG standard and BCH-NB-2007 protocol.
|
30793512 |
2019 |
Addictive Behavior
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Genetic studies suggest that the CHN2 gene harbors variants that contribute to addiction vulnerability and smoking behavior.
|
23941981 |
2013 |
Alcohol problem
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The current study proposes a step-by-step approach for using inverse propensity score weighting together with the "Bolck, Croon, and Hagenaars" approach to LCA with distal outcomes (i.e., the BCH approach), in order to estimate the causal effects of reasons for alcohol use latent class membership during the year after high school (at age 19) on later problem alcohol use (at age 35) with data from the longitudinal sample in the Monitoring the Future study.
|
29542004 |
2019 |
Central neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Therapy regime and risk classification were based on COG standard and BCH-NB-2007 protocol.
|
30793512 |
2019 |
Hepatosplenic T-cell lymphoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Finally, our study confirms the previously described gene expression profile of HSTL and identifies a set of 24 genes, including three located on chromosome 7 (CHN2, ABCB1 and PPP1R9A), distinguishing HSTL from other malignancies.
|
25057852 |
2014 |
Human immunodeficiency virus (HIV) II infection category B1
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Oral administration of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652), a nucleoside analog structurally similar to lamivudine (3TC), caused dose-dependent inhibition of viral replication in SCID-hu Thy/Liv mice infected with human immunodeficiency virus type 1 NL4-3 and with an NL4-3 clone containing the M184V mutation in reverse transcriptase that confers resistance to 3TC.
|
10681360 |
2000 |
Childhood Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Therapy regime and risk classification were based on COG standard and BCH-NB-2007 protocol.
|
30793512 |
2019 |
Sporadic CJD
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A SNP in the CHN2 gene was associated with vCJD [P = 1.5 × 10(-7); odds ratio (OR), 2.36], but not in UK sCJD (P = 0.049; OR, 1.24), in German sCJD or in PNG groups.
|
22210626 |
2012 |
Liver neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
Precancerous Conditions
|
0.300 |
Biomarker
|
group |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
Condition, Preneoplastic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
Malignant neoplasm of liver
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
Leukemia, Myelocytic, Acute
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
Other and unspecified reactive psychosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of atypical psychosis.
|
24132900 |
2013 |
Psychotic Disorders
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association study of atypical psychosis.
|
24132900 |
2013 |
Adolescent idiopathic scoliosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
Mammary Neoplasms
|
0.010 |
Biomarker
|
group |
LHGDN |
Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin.
|
15863513 |
2005 |
Diabetic Nephropathy
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.
|
19252134 |
2009 |