CHRM3, cholinergic receptor muscarinic 3, 1131

N. diseases: 284; N. variants: 17
Disease: Constipation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009806
Disease: Constipation
Constipation 		0.130 GeneticVariation phenotype BEFREE Generalized linear univariate model analysis performed on the opiate-induced constipation-associated SNPs and a single CHRM3 SNP revealed an association between anticholinergic symptoms and a score of 8 SNPs (adjusted P = 0.038, permuted P = 0.002). 29620694 2018
CUI: C0009806
Disease: Constipation
Constipation 		0.130 Biomarker phenotype BEFREE The control and constipation group received 1× PBS under the same pattern. 30122898 2018
CUI: C0009806
Disease: Constipation
Constipation 		0.130 Biomarker phenotype BEFREE Excess risk of IC/PBS was observed in the first- and second-degree relatives in probands with myalgia and myositis/unspecified (fibromyalgia) and in probands with constipation. 25349937 2016
CUI: C0009806
Disease: Constipation
Constipation 		0.130 Biomarker phenotype HPO