CHRM3, cholinergic receptor muscarinic 3, 1131

N. diseases: 284; N. variants: 17
Disease: Prune Belly Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 Biomarker disease BEFREE Animals received four weekly injections of either PBS (G1), ConvitVax (200 μg cell homogenate, 0.0625 mg BCG, 0.02% formalin) (G2), 50 μg anti-PD-1 (G3), or ConvitVax plus anti-PD-1 (200 μg cell homogenate, 0.0625 mg BCG, 0.02% formalin, 50 μg anti-PD-1) (G4). 31762937 2019
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 GeneticVariation disease BEFREE Finally, in a murine model of type 1 diabetes, NTA-modified complex micelles loading an insulin (NTA-CM-INS) group exhibited a long hypoglycemic effect which is superior to that of free insulin in the PBS (PBS-INS) group and insulin-loaded complex micelles without an NTA modification (CM-INS) group. 30212220 2018
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 Biomarker disease BEFREE T2DM mouse model was induced by high-fat-diet, and the mice were treated with fenofibrate (100 mg/kg) (DIO-FENO) or PBS (DIO-PBS) for 4 weeks. 29029615 2017
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 Biomarker disease BEFREE Here, we employed BALB/c ByJ mice inflected with SP, IAV, IAV followed by SP (IAV+SP) and PBS (Control) as models to survey the global gene expression using digital gene expression (DGE) profiling. 29348862 2017
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 GermlineCausalMutation disease ORPHANET We here describe a muscarinic acetylcholine receptor M3 (CHRM3) (1q41-q44) homozygous frameshift mutation in familial congenital bladder malformation associated with a prune-belly-like syndrome, defining an isolated gene defect underlying this sometimes devastating disease. 22077972 2011
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 Biomarker disease CTD_human We here describe a muscarinic acetylcholine receptor M3 (CHRM3) (1q41-q44) homozygous frameshift mutation in familial congenital bladder malformation associated with a prune-belly-like syndrome, defining an isolated gene defect underlying this sometimes devastating disease. 22077972 2011
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 GeneticVariation disease BEFREE Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome. 22077972 2011
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 Biomarker disease HPO
CUI: C0033770
Disease: Prune Belly Syndrome
Prune Belly Syndrome 		0.650 CausalMutation disease CLINVAR