MGLL, monoglyceride lipase, 11343

N. diseases: 125; N. variants: 7
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease BEFREE In this study, the cytotoxic and genotoxic activities of four MG congeners (MG FR3, MG GH787, cyanostatin B, MGL 402) and a well characterized cyanobacterial extract B-14-01 containing these metabolites were evaluated in the human hepatocellular carcinoma (HepG2) cell line. 31542581 2020
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE Further studies indicated that KLF4 directly bound to the promoter of MGLL and accelerated MGLL expression, which then led to HCC cell migration decrease. 30034939 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease BEFREE These results indicate that MAGL could be a potentially novel therapeutic target and prognostic indicator for HCC. 27767105 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE MGLL expression was detected in normal human hepatocytes and mouse liver, although it was undetected in human HCC cell lines. 26997225 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE The expression of MAGL was significantly higher in HCC tumors than in matched peritumor tissues. 27884159 2016