Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use
0.020 GeneticVariation disease BEFREE We tested whether response to a substance use prevention/intervention program varies based upon a set of five markers (rs16969968, rs1948, rs578776, rs588765, and rs684513) within the cluster of nicotinic acetylcholine receptor subunit genes (CHRNA5/A3/B4). 25941207 2016
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use
0.020 Biomarker disease BEFREE Taken together, our study provides evidence for a general role of the CHRNA5/A3/B4 gene cluster in substance use initiation that is not limited to nicotine and alcohol. 22382757 2012