C1QTNF6, C1q and TNF related 6, 114904

N. diseases: 33; N. variants: 5
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE However, the association between circulating CTRP6 and obesity in humans is still unclear. 31412378 2019
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE CTRP6 knockdown also upregulated expression of mitochondrial metabolic factors NRF-1, TFAM, CPT1 and Cyt C. Data from the current study show that CTRP6 knockdown protects against diet-induced obesity and promotes brown adipogenesis by the p38MAPK/Hh signaling pathway in conjunction with the upregulation of brown fat markers and mitochondrial metabolic factors. 29366805 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE Together, these results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. 28726640 2017