Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE In this study, we have examined the ability of a novel sulfonated derivative of β-cyclodextrin (KS-6469) to inhibit the influenza virus A/WSN/33 (H1N1) infection in vitro and in vivo. 31720013 2020
CUI: C0021400
Disease: Influenza
Influenza
0.100 GeneticVariation disease BEFREE These lncRNAs were also induced by other two influenza H1N1 virus strains (A/WSN/1933 and A/Oklahoma/3052/09) and interferon β1. 30669933 2019
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE However, both retroviral and lentiviral particles were unstable when pseudotyped with the influenza virus WSN strain envelope proteins. 28535668 2017
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE In this study, the interaction of opioid agonists and human influenza A/WSN/33 (H1N1) virus was examined in human lung epithelial A549 cells. 26350582 2017
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE By using mass spectrometry, threonine 80 (T80) was identified as a novel phosphorylated residue in the NS1 of the influenza virus A/WSN/1933(H1N1). 27376632 2017
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE The recombinant CaIFN-λ (rCaIFN-λ) displayed potent antiviral activity on both homologous and heterologous animal cells in terms of inhibiting the replication of the New Jersey serotype of vesicular stomatitis virus (VSV), canine parvovirus, and influenza virus A/WSN/33 (H1N1), respectively. 24950142 2014
CUI: C0021400
Disease: Influenza
Influenza
0.100 GeneticVariation disease BEFREE By using mass spectrometry, we identified tyrosine 132 (Y132) as a phosphorylation site of the matrix protein (M1) of the influenza virus A/WSN/1933(H1N1). 23536660 2013
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE From the screen, 17 HPKs (NPR2, MAP3K1, DYRK3, EPHA6, TPK1, PDK2, EXOSC10, NEK8, PLK4, SGK3, NEK3, PANK4, ITPKB, CDC2L5 (CDK13), CALM2, PKN3, and HK2) were validated as essential for A/WSN/33 influenza virus replication, and 6 HPKs (CDK13, HK2, NEK8, PANK4, PLK4 and SGK3) were identified as vital for both A/WSN/33 and A/New Caledonia/20/99 influenza virus replication. 23805279 2013
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE In comparison with human seasonal influenza H1N1 (A/HK/54/98) and mouse adapted influenza H1N1 (A/WSN/33) viruses, the highly pathogenic influenza H5N1 virus (A/HK/483/97) was a more potent inducer of the chemokine, CXCL 10 (IP-10), while there was not a clear differential TNF-α protein expression pattern. 23226456 2012
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE To determine whether the cellular miRNAs play an important role in H1N1 influenza A viral infections, 3' untranslated region (UTR) reporter analysis was used to identify putative miRNA targets in the influenza virus genome, and virus proliferation analysis was used to detect the effect of the screened miRNAs on the replication of H1N1 influenza A virus (A/WSN/33) in MDCK cells. 20554777 2010
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE Since dendritic cells may play a key role in defense against influenza virus infection, we examined the effects of recombinant hemagglutinin (HA) proteins derived from mouse-adapted H1N1 (A/WSN/1933), swine-origin 2009 pandemic H1N1 (A/Texas/05/2009), and highly pathogenic avian influenza H5N1 (A/Thailand/KAN-1/2004) viruses on mouse myeloid dendritic cells (mDCs). 20844030 2010
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE To understand viral genetic determinants responsible for this hyperinduction of cytokines, we constructed recombinant viruses containing different combinations of genes from high-cytokine (A/Vietnam/1203/04) and low-cytokine (A/WSN/33) phenotype H1N1 viruses and tested their cytokine-inducing phenotype in human macrophages. 19694514 2009
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE Viruses containing NS1 sequences from the 1918 H1N1 and H5N1 highly pathogenic avian influenza (HPAI) viruses demonstrated increased virulence in infected mice compared with wt A/WSN/33 virus, as characterized by rapid loss of body weight, decreased survival time, and decreased mean lethal dose. 18334632 2008
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE The associations between influenza and psychiatric disturbances in past epidemics are here commented upon, and the potentials of influenza to cause nervous system dysfunction in experimental infections with a mouse-neuroadapted WSN/33 strain of the virus are reviewed. 16459194 2006
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE For the present work, the functions of 101RKLKR105 were studied by introducing mutations into the M gene of influenza virus A/WSN/33 by reverse genetic methods. 15650216 2005
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE The initiation codons for the PB1 and NA proteins of A/WSN/33 (H1N1) influenza virus are in a suboptimal Kozak sequence for translation. 15019233 2004
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE Here we demonstrate, through the use of dominant-negative Rab5 and Rab7, that influenza virus (Influenza A/WSN/33 (H1N1) and A/X-31 (H3N2)) requires both early and late endosomes for entry and subsequent infection in HeLa cells. 12713661 2003
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE However, immunization of old and young mice with plasmids expressing the HA gene induced comparable clearance of influenza virus from the lungs and the same level of protection from a lethal challenge with live WSN influenza virus. 10532650 1999
CUI: C0021400
Disease: Influenza
Influenza
0.100 Biomarker disease BEFREE In this study, panels of monoclonal antibodies (Mabs) produced against the matrix proteins (M1) of A/WSN and A/PR/8/34 and the nucleoprotein (NP) of A/WSN were assessed for their value in identifying the hosts of origin of the M1 and NP genes in influenza virus isolates and in mapping the proteins' functional domains. 1626421 1992