Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0947751
Disease: Vascular inflammations
Vascular inflammations
0.010 Biomarker phenotype BEFREE Our results demonstrated that decrease of [Cl(-)](i) induced by ClC-3-dependent Cl(-) efflux promotes NF-κB activation and thus potentiates TNFα-induced vascular inflammation, suggesting that inhibition of ClC-3-dependent Cl(-) current or modification of intracellular Cl(-) content may be a novel therapeutic approach for inflammatory diseases. 23006728 2013