CMA1, chymase 1, 1215

N. diseases: 157; N. variants: 2
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 Biomarker group BEFREE Cellular Uptake of MCT1 Inhibitors AR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells. 30617815 2019
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 AlteredExpression group BEFREE MCT1 expression is elevated in glycolytic breast tumors, and high MCT1 expression predicts poor prognosis in breast and lung cancer patients. 26876179 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 Biomarker group BEFREE Accordingly, MCT-1 gene induction is recognized as a potential biomarker of breast tumor development. 24858043 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 AlteredExpression group BEFREE We also found that MCT1 expression was increased in human breast tumors harboring p53 mutations and coincident features of hypoxia, with higher MCT1 levels associated with poorer clinical outcomes. 22184616 2012