Disease: Alcohol Use Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 Biomarker disease BEFREE Findings support medium to large and unique associations of ALDH2, ADH1B, and ADH1C with AUD in East Asians. 30834931 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 GeneticVariation disease BEFREE The gene ADH1C, which has been previously implicated in AUD, was among our most significant associations (4.4 × 10<sup>-7</sup> ; rs141973904). 29058377 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 GeneticVariation disease BEFREE Two variants near ADH4 and 2 near ADH1C exhibited significant associations with AUD in AIs; no variant was significant in EAs. 28815635 2017
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 Biomarker disease BEFREE We evaluated the presence of SNPs in the ADH (ADH1B, ADH1C, and ADH4) and ALDH (ALDH2) genes in alcohol users of Goiânia, State of Goiás - Brazil, and then we established a possible relationship with AUD by allelic and genotypic study. 29084628 2017
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 GeneticVariation disease BEFREE For example, among those without protective alleles for ADH1B or ADH1C, OR for AUD was 1.87 as compared to those without the protective allele for ADH1B only and was 3.16 as compared to those with protective alleles for both ADH1B and ADH1C. 23895337 2013
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 Biomarker disease CTD_human Genetic associations of alcohol and aldehyde dehydrogenase with alcohol dependence and their mechanisms of action. 16404797 2005
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.360 GeneticVariation disease BEFREE Associations of alcohol dehydrogenase (ADH) gene polymorphisms (ADH1B*2 and ADH1C*1) with a lifetime alcohol use disorder (AUD) were examined in White college students. 16117582 2005