CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 GeneticVariation disease BEFREE <b>Background:</b> Several studies have revealed significant associations between single nucleotide polymorphisms (SNPs) in the cannabinoid receptor 1 (<i>CNR1</i>) gene and a broad spectrum of psychiatric disorders such as major depressive disorder (MDD), attention deficit hyperactivity disorder (ADHD), and schizophrenia. 29963071 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 GeneticVariation disease BEFREE Given the preclinical and clinical evidence regarding the associations between cannabinoid systems and both opiate dependence and psychiatric disorders, we chose to address whether one single nucleotide polymorphism (SNP) of the cannabinoid receptor type 1 gene (CNR1) named rs2023239 would be associated with lifetime MDD and SB in a population of opiate-dependent outpatients remitted under stable methadone treatment. 26331953 2015
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 Biomarker disease PSYGENET The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319 outpatients with MD and 150 healthy individuals. 23407780 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 GeneticVariation disease BEFREE The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319 outpatients with MD and 150 healthy individuals. 23407780 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 Biomarker disease PSYGENET The CB1 levels in the PFC of major depression patients were higher when compared to the age-matched controls (adj. p < 0.05). 22534181 2012
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 Biomarker disease PSYGENET We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 GeneticVariation disease BEFREE We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (rs1049353" genes_norm="1268">1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 Biomarker disease PSYGENET Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347 2008
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.350 GeneticVariation disease BEFREE Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347 2008