CNR2, cannabinoid receptor 2, 1269

N. diseases: 197; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.330 GeneticVariation disease BEFREE In the multivariate analysis, the CB2-RR variant (p = 0.03) and liver fibrosis were both identified as independent predictors of the entity of liver necroinflammation (p = 0.0001). 28759568 2017
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.330 Biomarker disease CTD_human Carbon tetrachloride-induced liver fibrosis was studied in mice invalidated for CB2 receptors. 15765409 2005
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.330 AlteredExpression disease BEFREE We recently showed that activation of hepatic cannabinoid CB2 receptors limits progression of experimental liver fibrosis. 16715087 2006
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.330 AlteredExpression disease BEFREE This study aimed to explore the relationship between liver fibrosis and the expression of CB1 and CB2 in patients with CHB. 28315398 2017