|
Fatty Liver
|
0.010 |
Biomarker
|
disease |
BEFREE |
Multivariate analysis showed that CP, age, high density lipoprotein (HDL) and hemoglobin were independent predictors of HS, and CP, body mass index and HDL were independent predictors of moderate and severe HS.
|
31076363 |
2020 |
|
Hypocholesterolemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Compared with the control group, dietary copper supplementation significantly decreased serum cholesterol (P < 0.05) and significantly increased serum IL-6, ceruloplasmin, SOD, GSH-Px, and liver copper (P < 0.05).
|
31119639 |
2020 |
|
HELLP Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, there was a positive correlation between the serum Cu and CP levels and the systolic and diastolic blood pressure values and aspartate amino transferase levels (AST), and a negative correlation between the serum Cu and CP levels and the platelet count.<b>Conclusion:</b> This was the first study in which the ceruloplasmin and Cu levels were investigated in HELLP syndrome patients.
|
29886772 |
2020 |
|
Fulminant Wilson's disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our study demonstrated that biochemical markers offer almost as reliable, fast and accurate diagnosis of FWD as offered by ceruloplasmin and 24-hour urinary copper.
|
31568639 |
2020 |
|
Malignant neoplasm of ovary
|
0.010 |
Biomarker
|
disease |
BEFREE |
Delivery of si-LINC00176, oe-LINC00176, si-BCL3 and si-CP plasmids was conducted to explore the effects of LINC00176 on ovarian cancer.
|
31668012 |
2020 |
|
Steatohepatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Multivariate analysis showed that CP, age, high density lipoprotein (HDL) and hemoglobin were independent predictors of HS, and CP, body mass index and HDL were independent predictors of moderate and severe HS.
|
31076363 |
2020 |
|
Carcinoma, Ovarian Epithelial
|
0.010 |
Biomarker
|
disease |
BEFREE |
Delivery of si-LINC00176, oe-LINC00176, si-BCL3 and si-CP plasmids was conducted to explore the effects of LINC00176 on ovarian cancer.
|
31668012 |
2020 |
|
Mental disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Neurotrophin levels and oxidative stress markers such as ceruloplasmin and free thiols have been shown to contribute to pathophysiology in several psychiatric disorders.
|
31779002 |
2019 |
|
Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Importantly, CP expression correlates with sensitivity to PAX8 silencing and identifies a subset of RCC cases with poor survival.
|
31431624 |
2019 |
|
Diabetic Nephropathy
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Previously we found that kidney tissue and urinary exosomes from patients of diabetic kidney disease showed high levels of ceruloplasmin (CP).
|
30955187 |
2019 |
|
Membranous glomerulonephritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
To investigate this hypothesis, we first measured urine exosomal and kidney expression of CP in non-diabetic chronic kidney disease (CKD) patients (membranous nephropathy, focal segmental glomerulosclerosis, lupus nephritis and IgA nephropathy) followed by a longitudinal study in rat passive Heymann nephritis (PHN), a model of human membranous nephropathy.
|
30955187 |
2019 |
|
Focal glomerulosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
To investigate this hypothesis, we first measured urine exosomal and kidney expression of CP in non-diabetic chronic kidney disease (CKD) patients (membranous nephropathy, focal segmental glomerulosclerosis, lupus nephritis and IgA nephropathy) followed by a longitudinal study in rat passive Heymann nephritis (PHN), a model of human membranous nephropathy.
|
30955187 |
2019 |
|
Hair Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
These results enhance our understanding of the function of HEPHL1 and implicate altered ferroxidase activity in hair growth and hair disorders.
|
31125343 |
2019 |
|
Hyperbilirubinemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The severity of his presentation and the disproportionately mild elevation in alkaline phosphatase relative to his hyperbilirubinaemia prompted repeating a ceruloplasmin level, which, though previously normal, was now low, and eventually led to a diagnosis of Wilson disease (WD) with concomitant alcoholic liver disease.
|
31653639 |
2019 |
|
Agenesis of corpus callosum
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among them, reduced expression levels of ferroportin1 (FPN1) and ceruloplasmin (CP) were significantly correlated with poor survival of ACC patients.
|
31442954 |
2019 |
|
Adrenocortical carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Reduced expression of ferroportin1 and ceruloplasmin predicts poor prognosis in adrenocortical carcinoma.
|
31442954 |
2019 |
|
Abnormal behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Neurotrophin levels and oxidative stress markers such as ceruloplasmin and free thiols have been shown to contribute to pathophysiology in several psychiatric disorders.
|
31779002 |
2019 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Importantly, CP expression correlates with sensitivity to PAX8 silencing and identifies a subset of RCC cases with poor survival.
|
31431624 |
2019 |
|
Aplasia Cutis Congenita
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among them, reduced expression levels of ferroportin1 (FPN1) and ceruloplasmin (CP) were significantly correlated with poor survival of ACC patients.
|
31442954 |
2019 |
|
Aortic valve disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Increased expression of H-ferritin accompanied by elevation of TNF-α (tumor necrosis factor-α) and IL-1β (interleukin-1β) levels, inducers of H-ferritin, corroborates the essential role of ferritin/ferroxidase via attenuating inflammation in calcific aortic valve disease.
|
30700131 |
2019 |
|
Chronic Kidney Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Urine exosomal CP levels were 10-20 times higher in CKD patients than in controls; consistent with this we found high immune-reactive CP localized in tubules and collecting ducts of biopsies of CKD patients.
|
30955187 |
2019 |
|
Venous Thromboembolism
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We assessed associations between CP and venous thromboembolism (VTE) risk in 9933 individuals.
|
30803124 |
2019 |
|
Alopecia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Investigation of oxidative stress in patients with alopecia areata by measuring the levels of malondialdehyde and ceruloplasmin in the blood.
|
30618523 |
2018 |
|
Alopecia Areata
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Investigation of oxidative stress in patients with alopecia areata by measuring the levels of malondialdehyde and ceruloplasmin in the blood.
|
30618523 |
2018 |
|
Cerebral Infarction
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ceruloplasmin Plays a Neuroprotective Role in Cerebral Ischemia.
|
30670944 |
2018 |