|
Withdrawal Symptoms
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The aim of this study was to investigate the effects of the selective A<sub>1</sub> receptor agonist CPA (N<sup>6</sup> -cyclopentyladenosine) on withdrawal symptoms, and the concentration of dopamine and noradrenaline in the nucleus accumbens and locomotor activity behavior during naloxone-precipitated withdrawal in morphine-dependent rats.
|
31808190 |
2020 |
|
Strawberry nevus of skin
|
0.010 |
Biomarker
|
disease |
BEFREE |
To assess the practicality of 3-D power Doppler angiography (3-D-CPA) for local drug perfusion dosage guidance of refractory infantile hemangioma (IH) treatment, 47 cases (48 lesions) of refractory IH were selected for local bleomycin infusion (once a month).
|
31810804 |
2020 |
|
internal lesion
|
0.010 |
Biomarker
|
disease |
BEFREE |
Three-dimensional CPA can provide abundant information on internal lesions.
|
31810804 |
2020 |
|
HEMIHYPERPLASIA, ISOLATED
|
0.010 |
Biomarker
|
disease |
BEFREE |
To assess the practicality of 3-D power Doppler angiography (3-D-CPA) for local drug perfusion dosage guidance of refractory infantile hemangioma (IH) treatment, 47 cases (48 lesions) of refractory IH were selected for local bleomycin infusion (once a month).
|
31810804 |
2020 |
|
Infantile hemangioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
To assess the practicality of 3-D power Doppler angiography (3-D-CPA) for local drug perfusion dosage guidance of refractory infantile hemangioma (IH) treatment, 47 cases (48 lesions) of refractory IH were selected for local bleomycin infusion (once a month).
|
31810804 |
2020 |
|
Rheumatoid Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
RA subgroups, according to the results of CRP and CPA, produce more and various information than taking RA as a whole group in the estimation of UTEs.
|
30171597 |
2019 |
|
Epilepsy
|
0.010 |
Biomarker
|
disease |
BEFREE |
In order to assess the effects of resveratrol, progesterone, oestradiol (E2), an anti-testosterone (cyproterone acetate; CPA), a selective ER modulator (tamoxifen; TMX) and ERα/ERβ agonists (propyl pyrazole triol (PPT), diarylpropionitrile (DPN)) on oxidative brain damage and memory impairment due to epileptic seizure, male Wistar rats (n = 120) received one of the treatment choices either in drinking water or intraperitoneally for 31 days, and epileptic seizure was induced on the 28th day by injection of a single-dose of pentylenetetrazole (45 mg kg<sup>-1</sup> ).
|
31608530 |
2019 |
|
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
In cases of patients that had a tumor that extended to the CPA, an unsatisfactory facial outcome was noted in 12 (30.0%) patients.
|
30987492 |
2019 |
|
Pancreatic Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
In contrast, similarly to the C57BL/6N mice, the <i>CPA1 null</i> control strain exhibited no signs of pancreatic disease.
|
30045879 |
2019 |
|
Memory impairment
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
In order to assess the effects of resveratrol, progesterone, oestradiol (E2), an anti-testosterone (cyproterone acetate; CPA), a selective ER modulator (tamoxifen; TMX) and ERα/ERβ agonists (propyl pyrazole triol (PPT), diarylpropionitrile (DPN)) on oxidative brain damage and memory impairment due to epileptic seizure, male Wistar rats (n = 120) received one of the treatment choices either in drinking water or intraperitoneally for 31 days, and epileptic seizure was induced on the 28th day by injection of a single-dose of pentylenetetrazole (45 mg kg<sup>-1</sup> ).
|
31608530 |
2019 |
|
Disorder of endocrine pancreas
|
0.010 |
Biomarker
|
group |
BEFREE |
Mutant mice were characterised with respect to pancreas pathology and ER stress and compared with C57BL/6N and <i>CPA1 null</i> control mice.
|
30045879 |
2019 |
|
Forgetful
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
In order to assess the effects of resveratrol, progesterone, oestradiol (E2), an anti-testosterone (cyproterone acetate; CPA), a selective ER modulator (tamoxifen; TMX) and ERα/ERβ agonists (propyl pyrazole triol (PPT), diarylpropionitrile (DPN)) on oxidative brain damage and memory impairment due to epileptic seizure, male Wistar rats (n = 120) received one of the treatment choices either in drinking water or intraperitoneally for 31 days, and epileptic seizure was induced on the 28th day by injection of a single-dose of pentylenetetrazole (45 mg kg<sup>-1</sup> ).
|
31608530 |
2019 |
|
Epileptic Seizures
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In order to assess the effects of resveratrol, progesterone, oestradiol (E2), an anti-testosterone (cyproterone acetate; CPA), a selective ER modulator (tamoxifen; TMX) and ERα/ERβ agonists (propyl pyrazole triol (PPT), diarylpropionitrile (DPN)) on oxidative brain damage and memory impairment due to epileptic seizure, male Wistar rats (n = 120) received one of the treatment choices either in drinking water or intraperitoneally for 31 days, and epileptic seizure was induced on the 28th day by injection of a single-dose of pentylenetetrazole (45 mg kg<sup>-1</sup> ).
|
31608530 |
2019 |
|
Arthralgia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In patients with arthralgia (n = 160), pCHIK-CPA longer than 6 weeks was reported by 44% and longer than 1 year by 26% of cases.
|
29709007 |
2018 |
|
Drug abuse
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Using the National Latino and Asian American Study we performed three-step logistic regressions to investigate LT-SUD for 1,427 Latinas, following three preplanned steps: (1) childhood physical and sexual abuse (CPA and CSA) with LT-SUD; (2) known correlates as controls; and (3) cultural strength factors.
|
29624121 |
2018 |
|
Exanthema
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Arthralgia, fever and skin rash were the dominant acute phase symptoms. pCHIK-CPA longer than 1 year affected 26% of cases and was predicted by female gender, high ACR-score and CHIKV-RNA detection beyond 7 days of symptom onset.
|
29709007 |
2018 |
|
Seizures
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The single-site mutants thus faithfully mimic the enzymatic properties of CPB and CPA, respectively. hCPO also shows a preference for Glu over Asp, probably as a consequence of a tighter fitting of the Glu side chain in its S1' substrate-binding pocket.
|
29636417 |
2018 |
|
Gestational Diabetes
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Pretreatment with EE/CPA was associated with a lower risk of GDM, PIH, and PD.
|
29525688 |
2018 |
|
Circadian Rhythm Disorders
|
0.010 |
Biomarker
|
disease |
BEFREE |
Also, since <i>d</i>-CPA and ketotifen have been widely used (e.g., to treat allergy and inflammation) in our daily life and thus raise a possible cause for circadian rhythm disorders by improper use of antihistamines.
|
29615980 |
2018 |
|
Peri-Implantitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The top five highly cited terms with > 500 publication counts were peri-implantitis (a mean of 20.17 citations per surveyed article [CPA]), survival rate (19.02 CPA), survival (18.74 CPA), implant failure (16.58 CPA), and success rate (16.53 CPA).
|
30427954 |
2018 |
|
Meningioma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Meningioma involving internal auditory canal was only seen in one of the six patients with CPA meningioma.One tumor was totally ossified.
|
28247112 |
2017 |
|
Mycoses
|
0.010 |
Biomarker
|
group |
BEFREE |
The conspicuous presence of CPA and its numerous derivatives in <i>A. flavus</i> cultures raises concerns about the long-term and cumulative toxicological effects of these fungal secondary metabolites and their contributions to the entire <i>A. flavus</i> mycotoxin problem.
|
28098779 |
2017 |
|
Inflammatory pain
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In addition, mechanical hyperalgesia was significantly reduced in the N6-cyclopentyladenosine (CPA) i.p. or i.m. and endomorphin (EM) i.p. groups.Neither EM i.m. nor EM i.p. exhibited any analgesic effect on thermal hyperalgesia.However, both CPA i.m. and CPA i.p. attenuated thermal hyperalgesia in the mouse inflammatory pain model.
|
29142219 |
2017 |
|
Adult Meningioma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Meningioma involving internal auditory canal was only seen in one of the six patients with CPA meningioma.One tumor was totally ossified.
|
28247112 |
2017 |
|
Idiopathic chronic pancreatitis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Herein we performed targeted next-generation sequencing of the CPA1 gene in 1,112 Han Chinese idiopathic chronic pancreatitis (ICP) patients-the largest ICP cohort so far analyzed in a single population-and 1,580 controls.
|
28497564 |
2017 |