CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019069
Disease: Hemophilia A
Hemophilia A
0.030 Biomarker disease BEFREE The TAFI pathway impairment correlates with bleeding phenotype in severe hemophilia and may represent a promising tool to stratify the bleeding risk. 31571361 2020
CUI: C0019069
Disease: Hemophilia A
Hemophilia A
0.030 Biomarker disease BEFREE In conclusion, the functional TAFI deficiency in hemophilia drives maladaptive vascular remodeling in the joints after bleeding. 31465300 2019
CUI: C0019069
Disease: Hemophilia A
Hemophilia A
0.030 Biomarker disease BEFREE Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding. 30026184 2018