CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.050 Biomarker disease BEFREE Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood-brain barrier dysfunction. 29194929 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.050 AlteredExpression disease BEFREE Similarly, in general, with the increase of TAFI levels, the curve showed that the relative risk of ischemic stroke first increased and then decreased (p=0.0110). 28890533 2017
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.050 GeneticVariation disease BEFREE High functional CPB2 levels have been found to be associated with an increased risk for ischemic stroke. 18986391 2008
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.050 Biomarker disease BEFREE AP showed associations with all 4 major subtypes of ischemic stroke and intact TAFI to large vessel disease and cryptogenic stroke. 17272741 2007
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.050 AlteredExpression disease BEFREE Individuals with functional TAFI levels in the highest quartile had an increased risk of ischemic stroke compared with the lowest quartile [odds ratio (OR) 4.0, 95% confidence interval (CI): 1.6-9.8]. 16092924 2005