Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Collectively, our findings demonstrate that CR1 availability on the surface of RBCs modulates P. vivax invasion. 31221984 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE In addition, antibodies against CR1 and basigin were used to determine the contributions of these receptors to invasion. 25838264 2015
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE We will focus on the role of complement receptor 1 and its associated polymorphisms in malaria immune complex clearance, as a mediator of parasite rosetting and as an entry receptor for P. falciparum invasion. 25816986 2015
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 PosttranslationalModification phenotype BEFREE Treatment of breast cancer cells with a demethylating agent and histone deacetylase inhibitors reduced methylation of the CR-1 promoter and reactivated CR-1 mRNA and protein expression in these cells, promoting migration and invasion of breast cancer cells. 23129342 2013
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Complement receptor-type 1 (CR1, CD35) is the immune-adherence receptor, a complement regulator, and an erythroid receptor for Plasmodium falciparum during merozoite invasion and subsequent rosette formation involving parasitized and non-infected erythrocytes. 22506052 2012
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE These data demonstrate that CR1 mediates SA-independent erythrocyte invasion in P. falciparum field isolates. 21251929 2011