CR2, complement C3d receptor 2, 1380

N. diseases: 123; N. variants: 9
Disease: Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 GeneticVariation disease BEFREE One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population. 29620631 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 Biomarker disease BEFREE The survival and lung tissue injury of the mice is observed and the effect of CR2 targeting complement inhibitors on pneumonia induced by influenza virus is evaluated. 20144216 2010
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 Biomarker disease HPO