CR2, complement C3d receptor 2, 1380

N. diseases: 123; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0086438
Disease: Hypogammaglobulinemia
Hypogammaglobulinemia
0.330 Biomarker disease GENOMICS_ENGLAND Both CD21 and CD19 deficiencies cause hypogammaglobulinemia and reduced memory B cells. 26325596 2015
CUI: C0086438
Disease: Hypogammaglobulinemia
Hypogammaglobulinemia
0.330 Biomarker disease BEFREE Genetic CD21 deficiency adds to the molecular defects observed in human subjects with hypogammaglobulinemia. 22035880 2012
CUI: C0086438
Disease: Hypogammaglobulinemia
Hypogammaglobulinemia
0.330 AlteredExpression disease BEFREE Expression of human complement receptor type 2 (CD21) in mice during early B cell development results in a reduction in mature B cells and hypogammaglobulinemia. 12244142 2002
CUI: C0086438
Disease: Hypogammaglobulinemia
Hypogammaglobulinemia
0.330 Biomarker disease BEFREE Cellular origins of serum complement receptor type 2 in normal individuals and in hypogammaglobulinaemia. 1849806 1991