CREM, cAMP responsive element modulator, 1390

N. diseases: 100; N. variants: 14
Disease: Hypertrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020564
Disease: Hypertrophy
Hypertrophy 		0.300 Therapeutic phenotype CTD_human Antisense inhibition of ICER significantly enhanced beta-adrenergic hypertrophy, whereas it significantly inhibited beta-adrenergic cardiac myocyte apoptosis, suggesting that endogenous ICER works as an important regulator of cardiac hypertrophy and apoptosis. 12791704 2003