Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
The changes in, and relationship between, plasma nitric oxide and corticotropin-releasing hormone in patients with major depressive disorder.
|
28755509 |
2018 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Corticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression.
|
29317606 |
2018 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association analysis for corticotropin releasing hormone polymorphisms with the risk of major depressive disorder and the response to antidepressants.
|
26055202 |
2015 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Evidence for the role of corticotropin-releasing factor in major depressive disorder.
|
26271720 |
2015 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our findings argue for a role of the SLC6A15 gene in ACTH and cortisol secretion during the Dex/CRH test and furthermore in the occurrence of cognitive impairments in unipolar depression.
|
22475622 |
2013 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder.
|
23529111 |
2013 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Our findings argue for a role of the SLC6A15 gene in ACTH and cortisol secretion during the Dex/CRH test and furthermore in the occurrence of cognitive impairments in unipolar depression.
|
22475622 |
2013 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene influences fMRI signal responses during emotional stimulus processing.
|
22378896 |
2012 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
In addition, persistent elevation of cerebrospinal fluid (CSF) corticotropin-releasing factor (CRF) concentrations following early-life adversity has been posited to underlie the subsequent development of major depression.
|
20692103 |
2011 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Our results suggest that the aberrant REST-mediated transcriptional regulation of, at least, CRH, adenylate cyclase 5, and tumor necrosis factor superfamily, member 12-13, might be state-dependent and associated with the pathophysiology of major depression.
|
19846118 |
2010 |
Unipolar Depression
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We found reduced mRNA expression of REST and increased mRNA expression of CRH, adenylate cyclase 5, and the tumor necrosis factor superfamily, member 12-13 in patients with major depressive disorder in a current depressive state, but not in a remissive state.
|
19846118 |
2010 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
CTD_human |
Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes.
|
18698320 |
2009 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Many pieces of evidence supported that corticotropin-releasing hormone (CRH) play a role in the pathophysiology of major depression.
|
16815632 |
2006 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
A function test combining the pre-treatment of 1.5 mg dexamethasone (DEX) with a challenge of 100 microg corticotropin-releasing hormone (CRH) reveals a pathological increase in the adrenocorticotropin and cortisol release in patients with major depression.
|
15504420 |
2005 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
CRH, stress, and major depression: a psychobiological interplay.
|
15196881 |
2004 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Recent research suggests that central corticotropin releasing hormone hyperdrive is an important neurobiological risk factor for developing major depression.
|
14573312 |
2003 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
CTD_human |
Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates.
|
12438692 |
2002 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
This differential effect of glucocorticoid on CRH mRNA regulation could help explain the abnormal CRH production observed in clinical disorders such as anorexia nervosa and major depression.
|
1547737 |
1992 |