CRH, corticotropin releasing hormone, 1392

N. diseases: 402; N. variants: 2
Disease: Anhedonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.320 Biomarker disease BEFREE This neurotransmitter plasticity is activity-dependent, as was revealed by chemogenetic manipulation of the central amygdala, a stress-sensitive nucleus that forms a major input to the DR. Activation of amygdalar corticotropin releasing hormone (CRH)+ neurons abolished the increase in DRv TPH2+ neurons and ameliorated stress-induced anhedonia in susceptible rats. 31792153 2020
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.320 AlteredExpression disease BEFREE We employed viral-genetic approaches to reduce corticotropin-releasing hormone (Crh) expression in the central nucleus of the amygdala in anhedonic rats, and tested for anhedonia reversal in the same animals. 29033027 2018
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.320 Biomarker disease PSYGENET Increased corticotropin-releasing factor concentrations in the bed nucleus of the stria terminalis of anhedonic rats. 10915835 2000