CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE High-sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death. 31350553 2020
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Longitudinal patterns of N-terminal pro B-type natriuretic peptide, troponin T, and C-reactive protein in relation to the dynamics of echocardiographic parameters in heart failure patients. 31596459 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Women had a lower risk for HF than men.Sex differences were seen for systolic blood pressure, heart rate, CRP, and NT-proBNP, with a lower HF risk in women. 30819375 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Several factors were associated with positive D-dimer results potentially falsely indicating thromboembolic disease in multivariate analysis including advanced age (odds ratio [OR] 1.04, 95% confidence interval [CI] 1.04-1.05, p < 0.001), congestive heart failure (CHF) (OR 2.79, 95% CI 1.77-4.4, p < 0.01), renal failure (OR 2.00, 95% CI 1.23-3.24, p = 0.005), history of malignancy (OR 2.6, 95% CI 1.57-4.31, p < 0.001), C-reactive protein (CRP) (OR 1.02, 95% CI 1.01-1.02, p < 0.001) and glomerular filtration rate (GFR) (OR 0.99, 95% CI 0.99-1.00, p = 0.003). 31339853 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Were performed quality of life (Minnesota Living with Heart Failure Questionnaire-MLHFQ) and sleep questionnaires (Epworth, Pittsburgh Sleep Quality Index-PSQI), serum B-type natriuretic peptide (BNP), serum C-reactive protein, transthoracic echocardiography, cardiopulmonary exercise test and overnight polysomnography immediately before and six months after pericardiectomy. 31603935 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE We undertook metabolomic and lipidomic phenotyping of a cohort of heart failure (HF) patients and utilized Multiple Regression Analysis (MRA) to identify associations to CPET and HFBio test performance (peak oxygen consumption (Peak VO2), oxygen uptake efficiency slope (OUES), exercise duration, and minute ventilation-carbon dioxide production slope (VE/VCO2 slope), as well as the established HF biomarkers of inflammation C-reactive protein (CRP), beta-galactoside-binding protein (galectin-3), and N-terminal prohormone of brain natriuretic peptide (NT-proBNP)). 31220103 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Gold-nanorod enhances dielectric voltammetry detection of c-reactive protein: A predictive strategy for cardiac failure. 30716591 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 AlteredExpression disease BEFREE Our meta-analysis suggests that iron therapy can reduce heart failure hospitalization, increase cardiac function, improve quality of life, and decrease serum levels of NT-proBNP and CRP in patients with heart failure. 30853478 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 AlteredExpression disease BEFREE However, despite low arterial lactate, patients with a high APACHEⅡ score, high C-reactive protein levels, and chronic heart failure had a poorer prognosis. 28923305 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Efficient electron-mediated electrochemical biosensor of gold wire for the rapid detection of C-reactive protein: A predictive strategy for heart failure. 31400725 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE After multivariable adjustment for clinical variables and renal and CV biomarkers (estimated glomerular filtration rate, cystatin-C, urine albumin-to-creatinine ratio, FGF-23, high-sensitivity troponin T, N-terminal pro-B-type natriuretic peptide, and high-sensitivity C-reactive protein), low Klotho concentration remained strongly associated with increased risk of CV death or hospitalization for heart failure [adjusted hazard ratio (HR) 2.62; 95% confidence interval (CI) 1.35-5.08; P < 0.01]. 30773798 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 AlteredExpression disease BEFREE Vitamin D supplementation in patients with CHF improved health-related quality of life and C-reactive protein levels [weighted mean difference (WMD): 6.75, 95% confidence interval (CI): 2.87 to 10.64, <i>p</i> < .001; standardised mean difference (SMD): -0.41, 95% CI: -0.71 to -0.11, <i>p</i> = .007]. 31032644 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE We examined 2184 consecutive patients with previous MI and CRP data at baseline in the Chronic Heart Failure Registry and Analysis in the Tohoku district-2 (CHART-2) Study. 31358306 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 GeneticVariation disease BEFREE Furthermore, temporal changes in CRP levels were associated with cancer death in the overall cohort; HF patients with CRP ≥ 2.0 mg/L at both baseline and 1-year had significantly increased cancer death, while those with CRP ≥ 2.0 mg/L at baseline and < 2.0 mg/L at 1-year not. 31104823 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE The aim of this study was to investigate the predictive value of single and repeated measurements of GDF-15 compared to Cystatin C and CRP for incidence of heart failure (HF) and death due to coronary heart disease (CHD) in the general population. 29771963 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Older age, atrial fibrillation, hypertension, obesity, edema, high C-reactive protein, and smoking were risk factors for HF. 29934374 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE In the multivariable analysis, the independent predictors of death were age (odds ratio (OR) 1.07, 95% confidence interval (CI) 1.02-1.13), C-reactive protein (CRP) at hospital admission (OR 1.12, 95% CI 1.04-1.21), length of the vegetation at diagnosis (OR 1.15, 95% CI 1.03-1.28), development of heart failure (OR 6.43, 95% CI 2.14-19.33), and embolic events during antimicrobial therapy (OR 12.14, 95% CI 2.11-71.89). 29382606 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE In the multivariable analysis, higher vWF concentrations (middle tertile hazard ratio [HR] 4.59, 95% confidence interval [CI] 1.55-13.50 [P=0.006]; upper tertile HR 4.10, 95% CI 1.43-11.75 [P=0.009]), age≥75years (HR 5.02, 95% CI 1.53-16.49; P=0.008), heart failure (HR 2.05, 1.01-4.19; P=0.048), C-reactive protein, log<sub>2</sub> per unit increase (HR 1.29, 95% CI 1.04-1.61; P=0.021), no warfarin at discharge (HR 4.96, 95% CI 2.02-12.20; P<0.0001) and no aspirin at discharge (HR 4.41, 95% CI 1.71-11.97; P=0.002) were independently associated with an increased risk of stroke and all-cause death, whereas female sex was a protective factor (HR 0.35, 0.16-0.78; P=0.01). 29685722 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Concerning death due to heart failure, NT-proBNP was associated with an 8-fold and C-reactive protein, GDF-15, and cystatin-C, with a 3-fold increase in risk. 30427997 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE Age, chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), forced expiratory volume in one second/ forced vital capacity (FEV1/FVC) ratio, duration of operation, hemoglobin, albumin and C-reactive protein (CRP) were potential risk factors for PPCs by univariate analysis. 30003856 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 GeneticVariation disease BEFREE Other predictors included ischemic etiology (HR 1.33, p=0.023), prior hospitalization for heart failure (HR 1.34, p=0.017), C-reactive protein (HR 1.04, p<0.001), and statin use (HR 0.70, p=0.016). 29169753 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 AlteredExpression disease BEFREE Our results hint towards an association of less common CRP genetic variants with increased mortality risk, depressive symptoms and peripheral CRP levels in this population of HF patients thereby suggesting a possible role of the inflammatory system as link between poor prognosis in HF and depressive symptoms. 29627531 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE As a result, previous studies have not provided conclusive evidence of the prognostic value of CRP for post-infarct LVSD or HF. 29633232 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE High CLA% was associated with significantly reduced risk of HF after adjustment for HF risk factors and C-reactive protein (hazard ratio [95% confidence interval], 0.64 [0.43-0.96]; quartile 4 versus quartile 1). 29306896 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker disease BEFREE After multivariable adjustment for baseline clinical characteristics and established biomarkers (high-sensitivity troponin I, brain-type natriuretic peptide, and high-sensitivity C-reactive protein), FGF-23 concentration in the top quartile was independently associated with an increased risk of CV death or heart failure hospitalization (adjusted hazard ratio [HR], 2.35; 95% CI, 1.82-3.02; P < .001) and its individual components. 29710336 2018