CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE hs-CRP correlated significantly with SLEDAI-2K (<i>p</i> = .036), SDI (<i>p</i> = .00), anti-dsDNA titers (<i>p</i> = .034), diabetes (<i>p</i> = .005), and obesity (<i>p</i> = .027). hs-CRP and Hcy correlated with triglyceride (TG) levels (<i>p</i> = .032 and <i>p</i> < .001, respectively), TG/high-density lipoprotein cholesterol index (<i>p</i> = .020 and <i>p</i> = .001, respectively), and atherogenic index of plasma (<i>p</i> = .006 and <i>p</i> = .016, respectively). hs-CRP levels >3 mg/L correlated with SDI score (<i>p</i> = .012) and several CVD risk factors. 31763930 2020
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Our study suggests that women with PCOS have oxidative stress and elevated CRP irrespective of obesity. 30450993 2020
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Critically, we found that CRP levels statistically mediated the relationships between obesity/greater BMI and working memory, with CRP accounting for 44.1% of the variance explained in working memory by BMI. 31785398 2020
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE CRP but not leukocyte count predicts early anastomotic healing after obesity surgery. 31784329 2020
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE The urinary CRP and 8-isoprostane significantly correlated with the obesity measures (body mass index, waist circumference, and waist-to- height ratio) and ET-1, inflammatory, and oxidative markers. 31737180 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Systemic CRP concentrations are affected by periodontitis and obesity in men. 31343076 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE And CRP and its combination with obesity and hypertension were associated with increased risk of T2DM. 30872696 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE Serum CRP levels were significantly higher in women with obesity at all time points. 31012350 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Secondarily, cortisol stimulation will contribute to the development of central obesity which is known to facilitate the development of metabolic syndrome, including slightly increased levels of inflammatory biomarkers such as C-reactive protein and fibrinogen. 31177066 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE We examined both WBC count and CRP level, independently and in combination, as predictive markers for type 2 diabetes and also considered the influence of obesity and other individual characteristics on the relationship. 30895902 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Maternal obesity is associated with alteration of immunological factors concentrations in the human milk, such as C-reactive protein (CRP), leptin, IL-6, insulin, TNF-Alpha, ghrelin, adiponectin, and obestatin. 31174304 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE The presence of obesity at ≥ 2 follow-ups showed the highest mean values (SE) for IL-6 [2.45 (1.05)] and CRP [3.74 (1.11)] and the lowest mean value for adiponectin [8.60 (0.37)] (adjusted analyses, females) compared with other exposures; the highest mean of IL-6 [1.65 (1.05)] and CRP [1.78 (1.11)] and the lowest mean of adiponectin [9.98 (0.38)] were for the number of follow-ups with ≥2 exposures compared to those with no exposures at any follow-up (adjusted analyses, females). 31071114 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Articles measuring serum CRP postoperatively in patients with obesity undergoing bariatric surgery were included. 30895509 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE Patients with obesity showed elevated levels of C-reactive protein and lipopolysaccharide-binding protein as compared to non-obese subjects, but no differences were noted for gut permeability between these two groups. 30903427 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE The study included 201 patients.Significant factors associated with increased LOS include type 2 diabetes mellitus (P < 0.012), obesity (P < 0.001), raised C-reactive protein (P < 0.0001), raised white cell count (P < 0.0001), raised temperature (P < 0.0001), septic shock (P < 0.003), multiorgan failure (P < 0.01), extended-spectrum beta-lactamases or methicillin-resistant Staphylococcus aureus colonization (P < 0.04) and intensive care unit admission (P < 0.0004). 29415341 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE As many factors linked to obesity can modulate CRP in T2DM, we comprehensively revisited the cardiometabolic phenotype of patients with normal or raised CRP, taking into account the sexual dimorphism of its serum value. 31477553 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE The effects of curcumin supplementation on glycemic status, lipid profile and hs-CRP levels in overweight/obese women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled clinical trial. 31780025 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE In multivariable logistic regression analysis, RT-related pain was significantly associated with elevated pre-RT CRP (≥ 10 mg/L) alone (odds ratio (OR) = 2.44; 95% confidence interval (CI) = 1.02, 5.85); or combined with obesity (OR = 4.73; 95% CI = 1.41, 15.81) after adjustment for age and race/ethnicity. 31138314 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes; independent of obesity and C-reactive protein. 30255491 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE The levels of hs CRP had significant correlations (p <0.05) with obesity and metabolic variables among women. 30015514 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE Our findings suggest a significant association of lower scores in the physical domain of quality of life and the presence of obesity with high CRP serum levels. 30728031 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE Furthermore, overweight/obese individuals showed positive correlation of both plasma C-Reactive Protein and triglyceride/HDLc-index with LGI-Ob; and high LGI-Ob score was associated with greater hypertension (<i>p</i> = 0.047), Type 2 diabetes (<i>p</i> = 0.026), and metabolic risk (<i>p</i> = 0.021). 30704070 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker disease BEFREE C-reactive protein (CRP), interleukin (IL)-10, and leptin were all higher in the obese/OSAS group than in controls (P = .004, 0.026, and <0.001, respectively), and compared to OSAS-only patients, CRP (P = .013) and leptin (P = .002) levels were higher in the obese/OSAS group. 31688081 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 AlteredExpression disease BEFREE The present study prospectively assessed the following over 23 years: (1) the association of psychological and physiologic stress during captivity with elevated C-reactive protein (CRP) levels and metabolic syndrome (MetS), which includes hypertension; elevated levels of insulin, triglycerides, and fasting glucose; decreased levels of high-density lipoprotein cholesterol; and obesity and (2) the implication of PTSD trajectories in elevated CRP levels and MetS. 28994516 2019
CUI: C0028754
Disease: Obesity
Obesity
0.600 GeneticVariation disease BEFREE Obese teachers had lower intakes of anti-inflammatory nutrients (vitamin B-6, vitamin A and zinc)/food (onion) compared with non-obese teachers (p<0.05) and obesity was significantly associated with CRP (Odd ratio (OR)=5.5, 95% Confidence interval (CI) 1.2-24.1, p=0.02). 29222885 2019