|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our results may provide a strong basis for studying the role of CRP and miRNAs in ischemic heart disease.
|
31063484 |
2019 |
|
Myocardial Ischemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Univariate analysis revealed several short-term mortality-related predictors, including older age (OR 1.1, <i>P</i>=0.005), ischemic heart disease (OR 2, <i>P</i>=0.0197), higher creatinine level (OR 2.3, <i>P</i>=0.0043), and elevated CRP level and CRP-to-albumin ratio (OR 1.1, <i>P</i> < 0.0001; OR 1.0031, <i>P</i> < 0.0001, respectively).
|
31828049 |
2019 |
|
Myocardial Ischemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
CRP also activated mPTP opening and reduced mitochondrial membrane potential during myocardial ischemia/reperfusion.
|
30364730 |
2018 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The associations of serum n-6 polyunsaturated fatty acids with serum C-reactive protein in men: the Kuopio Ischaemic Heart Disease Risk Factor Study.
|
29515239 |
2018 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
To test the hypothesis that the increased IHD risk because of obesity is mediated through lipoproteins, blood pressure, glucose, and C-reactive protein.
|
25411050 |
2015 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Using a multidirectional mendelian randomization design, we investigated possible causal associations between the lipoproteins and C-reactive protein and between the lipoproteins and IHD.
|
23926208 |
2013 |
|
Myocardial Ischemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We describe a significant proportion of individual TS females having high levels of vWF, factor VIII, fibrinogen and CRP (15-40%) and an increased frequency of the Leiden mutation, with important associations with CIMT and blood pressure, suggesting that a subset of TS may have an unfavourable haemostatic balance, which may contribute to the increased risk of premature ischaemic heart disease and possibly increase the risk of deep venous and portal vein thrombosis.
|
21848660 |
2012 |
|
Myocardial Ischemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Multivariate analyses indicated that the strongest associations with IHD and MI were due to the combined effect of the VEGFA-2578 A allele and smoking (OR 3.52 and 7.11, respectively), independent of risk factors such as age, sex, diabetes, C-reactive protein, hypercholesterolemia, and hypertension.
|
21362767 |
2011 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
RGD |
[Preliminary investigation of the changes and mechanism of Leptin after myocardial ischemia/reperfusion injury].
|
21122204 |
2010 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
We hypothesized that the CYP2C9(*)2 (rs.1799853) and CYP2C9(*)3 (rs.1057910) polymorphisms with decreased enzyme activity affect risk of subclinical atherosclerosis (reduced ankle brachial index and increased C-reactive protein), ischemic vascular diseases (ischemic heart disease, myocardial infarction, ischemic cerebrovascular disease and ischemic stroke) and death after an ischemic heart disease diagnosis.
|
19652664 |
2009 |
|
Myocardial Ischemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Genotype combinations of the four CRP polymorphisms were associated with an increase in CRP levels of up to 64%, resulting in a theoretically predicted increased risk of up to 32% for ischemic heart disease and up to 25% for ischemic cerebrovascular disease.
|
18971492 |
2008 |
|
Myocardial Ischemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The identification of polymorphisms that determine basal CRP levels has implications in ischaemic heart disease, where CRP level is an important predictor of risk.
|
14645206 |
2004 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The prevalence of C. pneumoniae DNA was not associated with age, gender, smoking, BMI, HDL, CRP, plasma creatinine and symptoms or signs of ischaemic heart disease.
|
14606608 |
2003 |
|
Myocardial Ischemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
After multivariate regression adjustment for age, race/ethnicity, body mass index, and family history of early-onset ischemic heart disease, physical fitness remained inversely associated with CRP level in boys (beta = -0.02; standard error = 0.01).
|
12563060 |
2003 |
|
Myocardial Ischemia
|
0.600 |
Biomarker
|
disease |
CTD_human |
Persistent elevation of C-reactive protein and ischemic heart disease in patients with continuous ambulatory peritoneal dialysis.
|
11840375 |
2002 |
|
Myocardial Ischemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Because of the importance of the CRP gene product in inflammation and its recent association with ischemic heart disease syndromes, this polymorphism may be useful in the association studies of atherosclerosis and its related phenotypes.
|
10721674 |
2000 |