Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Identified predictors of 4-year golimumab discontinuation were patient's global and female gender in patients overall and in subgroups of PsA and ax-SpA patients, and patient's global and CRP in RA.
|
31358361 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
However, patients who had a family history of RA and were ACPA positive showed significantly lower erythrocyte sedimentation rate, and C-reactive protein.
|
31620864 |
2020 |
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In this observational study, patients with untreated RA at risk of inadequate response to MTX included those with a higher TJC and higher CRP, while a higher TJC was the only independent predictor of an inadequate response to csDMARDs other than MTX.
|
30482075 |
2020 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
However, Midkine presents a significantly higher diagnostic accuracy (AUC=0.939) in detecting RA activity than that offered by C reactive protein (CRP) or ESR.
|
31324694 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In the full cohort and in RA, baseline and/or 12-month bone mineral density (BMD) at multiple sites exerted inverse relationships with CRP and βCTX, and positive correlation with SOST.
|
31522318 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Correlation between albumin to fibrinogen ratio, C-reactive protein to albumin ratio and Th17 cells in patients with rheumatoid arthritis.
|
31672633 |
2020 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
In comparison to controls, PE/E significantly increased systolic BP (MD = 8.3 mmHg, 95%CI 6.8 to 9.7), diastolic BP (MD = 6.8 mmHg, 95%CI 5.6 to 8.0), BMI (MD = 2.0 kg/m<sup>2</sup>; 95%CI 1.6 to 2.4), waist (MD = 4.3 cm, 95%CI 3.1 to 5.5), waist-to-hip ratio (MD = 0.02, 95%CI 0.01 to 0.03), weight (MD = 5.1 kg, 95%CI 2.2 to 7.9), total cholesterol (MD = 4.6 mg/dL, CI 1.5 to 7.7), LDL (MD = 4.6 mg/dL; 95%CI 0.2 to 8.9), triglycerides (MD = 7.7 mg/dL, 95%CI 3.6 to 11.7), glucose (MD = 2.6 mg/dL, 95%CI 1.2 to 4.0), insulin (MD = 19.1 pmol/L, 95%CI 11.9 to 26.2), HOMA-IR index (MD = 0.7, 95%CI 0.2 to 1.2), C reactive protein (MD = 0.05 mg/dL, 95%CI 0.01 to 0.09), and the risks of hypertension (RD = 0.24, 95%CI 0.15 to 0.33) and MetS (RD = 0.11, 95%CI 0.08 to 0.15).
|
31734276 |
2020 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
Multivariate linear regression analyses were performed to ascertain independent determinants of carotid stenosis severity, autonomic function, and inflammation.Systemic inflammation (C-reactive protein, beta = .255; P = .014), age (beta = .232; P < .008), and arterial hypertension (beta = .206; P = .032) were associated with carotid stenosis severity.
|
31093927 |
2020 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Deceased patients had a significantly higher age (mean 64.4 vs. 51.1 years); frequency of male sex (31.5% vs. 16.7%), hypertension (40.4 vs. 18.5%), and diabetes mellitus (25.8% vs. 7.7%); ESR (mean 57.1 vs. 43.0 mm/h); CRP (mean 16.9 vs. 8.7 mg/L); and FIB-4 (mean 1.5 vs. 1.0) (all P < 0.05) than the survivors.
|
30557057 |
2020 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
We compare the results of regressions of unemployment on self-reported health with those of regressions of unemployment on health as measured with biomarkers (hypertension and levels of blood glucose and C-reactive protein).
|
31805418 |
2020 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hsCRP]) in HIV-positive persons with CD4+ count >500 cells/mm3 is unknown.
|
31800000 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
hs-CRP correlated significantly with SLEDAI-2K (<i>p</i> = .036), SDI (<i>p</i> = .00), anti-dsDNA titers (<i>p</i> = .034), diabetes (<i>p</i> = .005), and obesity (<i>p</i> = .027). hs-CRP and Hcy correlated with triglyceride (TG) levels (<i>p</i> = .032 and <i>p</i> < .001, respectively), TG/high-density lipoprotein cholesterol index (<i>p</i> = .020 and <i>p</i> = .001, respectively), and atherogenic index of plasma (<i>p</i> = .006 and <i>p</i> = .016, respectively). hs-CRP levels >3 mg/L correlated with SDI score (<i>p</i> = .012) and several CVD risk factors.
|
31763930 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our study suggests that women with PCOS have oxidative stress and elevated CRP irrespective of obesity.
|
30450993 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Critically, we found that CRP levels statistically mediated the relationships between obesity/greater BMI and working memory, with CRP accounting for 44.1% of the variance explained in working memory by BMI.
|
31785398 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
CRP but not leukocyte count predicts early anastomotic healing after obesity surgery.
|
31784329 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
To compare the multi-biomarker disease activity (MBDA) score with the DAS28-CRP and CRP for predicting risk of radiographic progression in patients with rheumatoid arthritis.
|
30777458 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The RA group had higher CRP (P = 0.006), were more likely to receive glucocorticoids (P<0.001), and experienced worse fatigue (P = 0.050).
|
31170172 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Multivariate regression analysis demonstrated significant correlations between GLSs and RA duration (p = 0.02), and GLSs and DAS28-CRP (p = 0.041).
|
31843000 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The increase of blood platelet, and CRP levels and decrease of blood albumin are probable risk factors for PN in RA patients.
|
30911944 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In conclusion, IL-1β, IL-17A, CRP and biologics history would serve as potential markers for clinical response to ETN in RA patients.
|
31463666 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
To investigate serum interleukin (IL)- 35 levels in patients with rheumatoid arthritis (RA) and to describe the association between serum IL-35 levels and clinical parameters: erythrocyte sedimentation rate (ESR), C reactive protein (CRP), global health on Visual Analog Scale, Disease Activity Score in 28 joints based on ESR (DAS28-ESR), rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (ACPAs).
|
30659089 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Fifty-two percent developed RA.Foot tenosynovitis was predictive (OR 2.55, 95% CI 1.01-6.43), independent of BME and synovitis (OR 3.29, 95% CI 1.03-10.53), but not independent of CRP and number of swollen joints (OR 2.14, 95% CI 0.77-5.95).
|
30764871 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The plasma VEGF levels and VEGF expressions in CD4+ T, CD8+ T, and Treg subsets positively correlated with SDAI and CRP in RA patients.
|
31820713 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
At baseline, patients with established RA had a median DAS28 of 4.8 (3.2-8.3) and, compared to healthy controls, had higher plasma levels of CRP (p < 0.0001), FXIII (p = 0.017) and F1+2 (p < 0.0001).
|
31654331 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Of 5376 patients with RA enrolled in the Korean observational study network for arthritis (KORONA) registry, 400 patients with disease duration of <2 years who had Clinical Disease Activity Index (CDAI) score of >2.8 at baseline, biologic-naïve, and erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) drawn at both baseline and 2-year follow-up visits were identified.
|
30677239 |
2019 |