|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Cas proteins mediate integrin-dependent signals at focal adhesions, regulating cell invasion and survival; at least one family member, HEF1, regulates mitosis.
|
18256281 |
2008 |
|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer.
|
22450763 |
2012 |
|
Adenoma of large intestine
|
0.010 |
Biomarker
|
disease |
BEFREE |
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.
|
22711543 |
2012 |
|
Colorectal Carcinoma
|
0.360 |
Biomarker
|
disease |
BEFREE |
CSE1L, DIDO1 and RBM39 are located on the 20q amplicon and affect processes such as cell viability and anchorage-independent growth in colorectal cancer.
|
22711543 |
2012 |
|
Malignant neoplasm of colon and/or rectum
|
0.040 |
Biomarker
|
disease |
BEFREE |
CSE1L, DIDO1 and RBM39 are located on the 20q amplicon and affect processes such as cell viability and anchorage-independent growth in colorectal cancer.
|
22711543 |
2012 |
|
Carcinoma
|
0.030 |
AlteredExpression
|
group |
BEFREE |
CSE1L protein expression was not associated with 20q gain, although its expression was increased in carcinomas compared to adenomas.
|
22711543 |
2012 |
|
Diffuse Large B-Cell Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
CSE1L- and inhibitor of DNA binding-3 (ID3)-overexpression was associated with the diagnosis of BL and signal transduction and transcription-3 (STAT3) with DLBCL (P<0.001 for all markers).
|
22967991 |
2013 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression.
|
23806821 |
2013 |
|
Primary malignant neoplasm
|
0.070 |
Biomarker
|
group |
BEFREE |
CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression.
|
23806821 |
2013 |
|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression.
|
23806821 |
2013 |
|
Colorectal Carcinoma
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
CSE1L (chromosome segregation 1-like) gene maps to 20q13, a chromosomal region that correlates with colorectal cancer development.
|
23806821 |
2013 |
|
Malignant neoplasm of colon and/or rectum
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
CSE1L (chromosome segregation 1-like) gene maps to 20q13, a chromosomal region that correlates with colorectal cancer development.
|
23806821 |
2013 |
|
Neoplasm Metastasis
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
CSE1L knockdown reduced Ras-induced metastasis of B16F10 melanoma cells in C57BL/6 mice. v-H-Ras expression altered the cellular trafficking of CSE1L and increased CSE1L secretion.
|
23806821 |
2013 |
|
Malignant neoplasm of breast
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
CAS P8 -652 6N del polymorphism and breast cancer risk: a systematic review and meta-analysis.
|
24457433 |
2014 |
|
Breast Carcinoma
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
CAS P8 -652 6N del polymorphism and breast cancer risk: a systematic review and meta-analysis.
|
24457433 |
2014 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
CSE1L is involved in colon carcinogenesis.
|
27521996 |
2016 |
|
Adenoma
|
0.020 |
Biomarker
|
group |
BEFREE |
CSE1L was significantly increased during the transition from AD to CRC when compared with NR in a CRC tissue microarray (P = 0.01 and P < 0.001).
|
27521996 |
2016 |
|
Colorectal Carcinoma
|
0.360 |
Biomarker
|
disease |
BEFREE |
CSE1L was significantly increased during the transition from AD to CRC when compared with NR in a CRC tissue microarray (P = 0.01 and P < 0.001).
|
27521996 |
2016 |
|
Virus Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Cas proteins utilize these crRNAs, which contain spacer sequences that can be derived from mobile genetic elements, to mediate immunity during a reoccurring virus infection.
|
28238733 |
2017 |
|
Carotid Stenosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
CAS has emerged as an alternative to carotid endarterectomy for the treatment of significant carotid artery stenosis.
|
28474136 |
2017 |
|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
CAS is a docking protein downstream of the proto-oncogene Src with a role in invasion and metastasis of cancer cells.
|
28808245 |
2017 |
|
Neoplasm Metastasis
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
CAS is a docking protein downstream of the proto-oncogene Src with a role in invasion and metastasis of cancer cells.
|
28808245 |
2017 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
CAS-viewer: web-based tool for splicing-guided integrative analysis of multi-omics cancer data.
|
29697367 |
2018 |
|
Primary malignant neoplasm
|
0.070 |
Biomarker
|
group |
BEFREE |
CAS-viewer: web-based tool for splicing-guided integrative analysis of multi-omics cancer data.
|
29697367 |
2018 |
|
Multiple malignancy
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
CAS-viewer is a web-based application for transcript isoform-driven integration of multi-omics data in multiple cancer types and will aid in the visualization and possible discovery of biomarkers for cancer by integrating multi-omics data from TCGA.
|
29697367 |
2018 |