Acute lymphocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, bone marrow samples from 100 children with acute lymphoblastic leukemia (ALL) were cultured in the cytokines TNF-alpha, GM-CSF, c-kit ligand, and fetal liver tyrosine kinase 3 ligand, with or without IL-3 and -4 and after administration of HdI valproic acid (VAL), suberoylanilide hydroxamic acid (SAHA), isobutyramid, or trichostatin A.
|
19129484 |
2009 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our data indicate that immunization with B7.1/GM-CSF-expressing cell vaccines generated by electroporation and application of double stem-loop immunomodulating oligonucleotide protected mice against a murine Ph(+) ALL challenge.
|
12912966 |
2003 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Receptor-binding for myeloid-associated GF was observed in the majority of precursor B-ALL (G-CSF = 100%, GM-CSF = 65%, IL-3 = 83%, SCF = 74%), but not in T-ALL.
|
7535143 |
1994 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
To examine concentration of cerebrospinal fluid (CSF) biomarkers of brain injury at ALL diagnosis and during cancer therapy and to evaluate associations with long-term neurocognitive and neuroimaging outcomes and relevant genetic polymorphisms.
|
29596541 |
2018 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Expression and role of granulocyte macrophage colony-stimulating factor receptor (GM-CSFR) and granulocyte colony-stimulating factor receptor (G-CSFR) on Ph-positive acute B lymphoblastic leukemia.
|
29338593 |
2018 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Role of granulocyte-macrophage colony-stimulating factor in Philadelphia (Ph1)-positive acute lymphoblastic leukemia: studies on two newly established Ph1-positive acute lymphoblastic leukemia cell lines (Z-119 and Z-181).
|
8600166 |
1996 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We quantitatively assessed the expression of cytokine receptors (interleukin-2 receptor (IL-2R), IL-3R, IL-4R, IL-5R, IL-6R, IL-7R, granulocyte-macrophage colony-stimulating factor R (GM-CSFR), G-CSFR, c-fms, c-mpl, c-kit and FLT3) in cells from 211 adults with acute lymphoblastic leukemia (ALL) by flow cytometry and determined their prevalence and clinical significance.
|
17205058 |
2007 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage- colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses.
|
10942373 |
2000 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
COG AALL07P4 examined the asparaginase activity and plasma and CSF asparagine concentration of pegaspargase when given intravenously in the treatment of NCI high risk ALL.
|
30626253 |
2019 |
Acute lymphocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Purpose To determine the prognostic significance of blasts, and of white and red blood cells, in CSF samples at diagnosis of acute lymphoblastic leukemia (ALL), a uniform CSF and risk group classification schema was incorporated into Children's Oncology Group B-cell ALL (B-ALL) clinical trials.
|
28535084 |
2017 |
Acute lymphocytic leukemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
These findings prompted us to establish five ALL cell lines of diverse phenotypes to examine the expression of GM-CSF and GM-CSF receptor genes in human leukemia, and to determine the role of GM-CSF in autocrine and paracrine growth control of ALL cells.
|
8499641 |
1993 |