CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 GeneticVariation group BEFREE To test whether antitumor activity could be increased by combining the above two mechanisms, this study examined the therapeutic effect of combination gene therapy using a murine granulocyte-macrophage colony-stimulating factor (mGM-CSF) gene and a human endostatin (hED) gene on a rat orthotopic liver tumor model. 12731087 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 Biomarker group BEFREE The results showed that combined gene transfer of p21WAF-1 and GM-CSF could inhibit the growth of pre-established tumor more effectively and prolong the survival time of hepatoma-bearing mice more significantly than the transfer of a single gene. 11916239 2002
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 Biomarker group BEFREE Combination therapy with GM-CSF and IL-12 represents a promising immunotherapy strategy for treating orthotopic, widespread liver tumors. 17326190 2007
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 Biomarker group BEFREE The results demonstrated that combined administration of p21(WAF-1) and GM-CSF could remarkably inhibit the growth of subcutaneously transplanted hepatoma Hepa cells, and significantly increase the survival rate of tumor-bearing mice. 12833133 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 Therapeutic group CTD_human Combination therapy with GM-CSF and IL-12 represents a promising immunotherapy strategy for treating orthotopic, widespread liver tumors. 17326190 2007
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 AlteredExpression group BEFREE Therefore, these results suggest that combining expression of GM-CSF and B70 may enhance NK-mediated cytotoxicity, and then induce the antitumor immunity in hepatoma transplanted into nude mice. 11295284 2001
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 AlteredExpression group BEFREE The distant bystander effect was associated with a strong induction of GMCSF and IL-12 expression in the untreated TK-negative liver tumors. 11880183 2002