CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Biomarker group BEFREE A phase I study of recombinant (r) vaccinia-CEA(6D)-TRICOM and rFowlpox-CEA(6D)-TRICOM vaccines with GM-CSF and IFN-α-2b in patients with CEA-expressing carcinomas. 27581603 2016
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Biomarker group BEFREE Magmas, a conserved mammalian protein essential for eukaryotic development, is overexpressed in prostate carcinomas and cells exposed to granulocyte-macrophage colony-stimulating factor (GM-CSF). 20053669 2010
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Biomarker group BEFREE Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. 15613691 2005
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Biomarker group BEFREE Recent research found abnormal expression of the c-fms oncogene, which encodes the macrophage colony-stimulating factor receptor (CSF-1R), in several human carcinomas including hepatocellular carcinoma (HCC). 14969845 2004
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Therapeutic group CTD_human Chemoimmunotherapy of cancer: potentiated effectiveness of granulocyte-macrophage colony-stimulating factor and ifosfamide derivative CBM-4A. 11605069 2001
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 AlteredExpression group BEFREE Our data show that the LNCaP cells express functional GM-CSF receptors and that prostatic carcinomas have prominent GM-CSF receptor expression. 9446667 1998
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 Biomarker group BEFREE (c) Some, but not all, lung carcinomas produced this cytokine, and a close correlation was found between the production of GM-CSF and the number of CD1a+ LC infiltrating these tumors. 7679411 1993
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.370 AlteredExpression group BEFREE Only in LC-positive carcinomas did epithelial cells close to lymphoid aggregates display small amounts of GM-CSF and TNF alpha mRNA expression. 7635448 1995