CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE SEGAs may lead to impaired circulation of CSF resulting in hydrocephalus and raised intracranial pressure in patients with TSC. 31834371 2020
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Of these, 10.5% (39/373) required permanent CSF shunting due to persisting postoperative HC. 30120611 2020
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE These findings could represent a novel form of high-pressure hydrocephalus that can be successfully treated without a CSF shunt. 31025176 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 GeneticVariation disease BEFREE In non-syndromic CIM subjects, the presence of hydrocephalus could be explained by an occlusion of the basal CSF pathways, which would occur completely in a minority of cases (only 7-10% of CIM patients show hydrocephalus) while it would be partial in the remaining cases (no hydrocephalus). 31227858 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE We report the case of a 4-month-old baby with a wide optic-chiasmal hypothalamic glioma generating hydrocephalus with high protein values in CSF. 31049668 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Real-time MRI access to CSF flow in response to defined respiration patterns will be of clinical importance for patients with disturbed CSF circulation like hydrocephalus, pseudotumor cerebri and others. 30947716 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 GeneticVariation disease BEFREE PDC versus graft dural closure (GDC; 35% vs 7%, OR 5.88, 95% CI 2.94-50.0, p = 0.03) and hydrocephalus ultimately requiring permanent CSF diversion (OR 3.30, 95% CI 1.07-10.19, p = 0.0007) were associated with wound infection requiring surgical debridement. 31783365 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 AlteredExpression disease BEFREE Based on the changes in CSF levels of SP-G in hydrocephalus, brain hemorrhage, and CNS infections as well as its abundance at CSF flow-related anatomical structures closely associated with immunological barrier systems, importance for CSF rheology, brain waste clearance, and host defense is assumable. 30032421 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 GeneticVariation disease BEFREE Outcomes included symptomatic hydrocephalus requiring CSF drainage, need for ventriculoperitoneal shunt, radiographic vasospasm, delayed cerebral ischemia (DCI), radiographic infarction, disability level within 1 year of ictus, and at last clinical follow-up as defined by the modified Rankin Scale. 30996058 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE The most consistent indications for surgical intervention in early hydrocephalus were CSF leak from the back (92%), progressive ventricular enlargement (89%), and brainstem symptoms, including apnea/bradycardia (81%), stridor (81%), and dysphagia (81%). 31470398 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE The present study identified acute hydrocephalus with the necessity of CSF diversion as significant and independent risk factor for the development of shunt dependency during treatment course in patients suffering from non-aneurysmal SAH. 29594703 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Duraplasty (n = 101) was complicated by CSF leak in 4.0% (n = 4), symptomatic pseudomeningocele in 4.0% (n = 4), aseptic meningitis in 2.0% (n = 2) and hydrocephalus in 1.0% (n = 1). 30737652 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE The patient developed worsening intracranial hypertension after successful CSF diversion of Dandy-Walker malformation-associated hydrocephalus via endoscopic third ventriculostomy-choroid plexus cauterization (ETV/CPC). 30611152 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE We observed ventricular reflux of Gd-DOTA in SHR rats only, indicating abnormal CSF flow dynamics secondary to innate hydrocephalus. 31209176 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 GeneticVariation disease BEFREE Whilst 80% (50/61) of cases underwent FMD with no preceding or post-operative problems of CSF dynamics, 8% (5/61) of cases had hydrocephalus at initial presentation requiring CSF diversion followed by FMD for persistent Chiari, and 10% (6/61) developed hydrocephalus following FMD and required long-term CSF diversion. 31203396 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE For patients with ePFTs, petroclival/midline tumor location (OR 12.2/OR 5.7), perilesional edema (OR 10.0), and preoperative hydrocephalus (OR 4.0) were independent predictors of need for CSF drainage. 30611134 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Here, we report a case where a patient with subarachnoid haemorrhage (SAH) with acute hydrocephalus needed CSF diversion and had an EVD, during replacement of which through the same tract, the new EVD went into the sellar floor and she developed diabetes insipidus (DI) eventually. 31073783 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Although neonates and infants with group B streptococcal or <i>E coli</i> meningitis had similar age and CSF laboratory values, patients with group B streptococcal meningitis more frequently demonstrated infarcts, while those with <i>E coli</i> meningitis more frequently had early onset of hydrocephalus. 31320464 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Three patients (3.9%) underwent endoscopic biopsy and CSF diversion for cysts all more than 20mm with radiological evidence of hydrocephalus. 31264489 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE This case highlights the importance of prompt CSF diversion and cardiac support for acute hydrocephalus presenting with heart failure in the pediatric population. 31003226 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE On the other side, a positive mismatch, consisting of intracranial content higher than skull volume, usually depends on CSF collection or hydrocephalus once the brain edema is regressed. 31134339 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Three newborns developed signs of hydrocephalus requiring CSF diversion. 31574466 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Thus, areas can serve as a surrogate marker for total brain and CSF volumes for a quantitated objective tracking of changes during treatment of childhood hydrocephalus. 31834503 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE There was a significant association between CSF GeneXpert and Mantoux test (P = 0.002), CSF cell type >50% lymphocytes (P = 0.005) and CSF protein >100 mg/dl (P = 0.025) along with CT hydrocephalus (P = 0.021), granuloma (P = 0.009) and basal exudates (P = 0.025). 31359250 2019
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.100 Biomarker disease BEFREE Intraventricular endoscopic cyst drainage allows resolution of hydrocephalus with restoration of normal intracranial pressure, gives time for proper preoperative work up, and has reduced incidence of CSF leak after transnasal surgery. 29435609 2018