CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV
0.050 Biomarker disease BEFREE These findings support the hypothesis that GM-CSF and MMP9 promote the protumorigenic effect of WAT progenitors on local and metastatic breast cancer.<i></i>. 28754674 2017
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV
0.050 Biomarker disease BEFREE We also identified the osteoclast activators IL-11 and granulocyte-macrophage colony-stimulating factor (GM-CSF) as new target genes of Runx2/CBFβ in metastatic breast cancer cells. 22032690 2011
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV
0.050 Biomarker disease BEFREE Patients with HER2+ metastatic breast cancer that progressed after trastuzumab +/- chemotherapy were continued on trastuzumab 2 mg kg(-1) intravenous weekly and GM-CSF 250 μg m(-2) subcutaneous daily. 20877352 2010
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV
0.050 Biomarker disease BEFREE First, immunotherapy with an allogeneic, HER2-positive, GM-CSF-secreting breast tumor vaccine alone or with CY and DOX is safe and induces HER2-specific immunity in patients with metastatic breast cancer. 19805669 2009
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV
0.050 Biomarker disease BEFREE Objective clinical regression of metastatic breast cancer in disparate sites after use of whole-cell vaccine genetically modified to release sargramostim. 16958969 2008