CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 Biomarker phenotype BEFREE To evaluate the safety, recommended phase II dose (RP2D) and efficacy of pexidartinib, a colony stimulating factor receptor 1 (CSF-1R) inhibitor, in combination with weekly paclitaxel in patients with advanced solid tumors. 31258629 2019
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 Biomarker phenotype BEFREE In summary, Ad5/3-D24-GMCSF appears promising for the treatment of advanced STS; a clinical trial for treatment of refractory injectable solid tumors including STS is ongoing. 24374597 2014
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 Biomarker phenotype BEFREE The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors. 24565030 2014
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 Biomarker phenotype BEFREE Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. 21630267 2012
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 GeneticVariation phenotype BEFREE Subsequently, 20 patients with advanced solid tumors refractory to standard therapies were treated with Ad5-D24-GMCSF. 20484030 2010
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 Biomarker phenotype BEFREE An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors. 18670453 2009
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.070 AlteredExpression phenotype BEFREE This is the first report that demonstrates expression of the GM-CSF gene in solid tumors at the mRNA level. 3119535 1987